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Using Acetone/Water Binary Solvent to Enhance the Stability and Bioavailability of Spray Dried Enzalutamide/HPMC-AS Solid Dispersions Journal article
Journal of Pharmaceutical Sciences, 2021,Volume: 110,Issue: 3,Page: 1160-1171
Authors:  Zhang,Xiaoting;  Rao,Qiuhong;  Qiu,Zhenwen;  Lin,Yisheng;  Zhang,Lei;  Hu,Qingzhong;  Chen,Tingting;  Ma,Zhimin;  Gao,Hanlu;  Luo,Dandong;  Zhao,Jiaqi;  Ouyang,Defang;  Zhang,Zhenyu Jason;  Li,Qingguo
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Amorphous solid dispersion  Drug-excipient interaction  Particle size  Poorly water-soluble drug  Spray drying  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
European Journal of Pharmaceutics and Biopharmaceutics, 2021,Volume: 158,Page: 336-346
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Dissolution profile  Machine learning  molecular dynamics (MD) simulations  Pharmacokinetic modeling  Solid dispersion  
Simultaneous extraction, separation, isolation and identification of endogenous components from Etlingera elatior by pressurized matrix solid-phase dispersion using liquid chromatography–mass spectrometry Journal article
Journal of Chromatography A, 2020,Volume: 1611
Authors:  Ge,Liya;  Yong,Jean Wan Hong;  Tan,Swee Ngin;  Li,Shao Ping
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Etlingera elatior  LC–MS  NMR  Pressurized matrix solid-phase dispersion  Sample preparation  
Predicting physical stability of solid dispersions by machine learning techniques Journal article
Journal of Controlled Release, 2019,Volume: 311-312,Page: 16-25
Authors:  Han,Run;  Xiong,Hui;  Ye,Zhuyifan;  Yang,Yilong;  Huang,Tianhe;  Jing,Qiufang;  Lu,Jiahong;  Pan,Hao;  Ren,Fuzheng;  Ouyang,Defang
Favorite |  | TC[WOS]:22 TC[Scopus]:22 | Submit date:2021/03/02
Machine learning  Molecular modeling  Physical stability  Solid dispersion  
Molecular Interactions for the Curcumin-Polymer Complex with Enhanced Anti-Inflammatory Effects Journal article
PHARMACEUTICS, 2019,Volume: 11,Issue: 9
Authors:  Yan He;  Hongfei Liu;  Wangqing Bian;  Yue Liu;  Xinyang Liu;  Shijing Ma;  Xi Zheng;  Zhiyun Du;  Kun Zhang;  Defang Ouyang
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2020/03/25
Curcumin  Polyvinylpyrrolidone (Pvp)  Solid Dispersions  Molecular Modeling  Drug-polymer Interactions  
Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
AAPS PHARMSCITECH, 2019,Volume: 20,Issue: 7
Authors:  Run Han;  Tianhe Huang;  Xinyang Liu;  Xinyang Liu;  Haifeng Li;  Jiahong Lu;  Yuanhui Ji;  Huimin Sun;  Defang Ouyang
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2020/03/25
Solid Dispersion  Dissolution Effect  Molecular Modeling  Ternary System  
Monodisperse molecularly imprinted microsphere cartridges coupled with HPLC for selective analysis of dexamethasone and hydrocortisone in cosmetics by using matrix solid-phase dispersion Journal article
ANALYTICAL METHODS, 2019,Volume: 11,Issue: 29,Page: 3687-3696
Authors:  Pengqi Guo;  Guoning Chen;  Hua Shu;  Peng Li;  Pei Yu;  Chun Chang;  Yitao Wang;  Qiang Fu
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2019/11/22
Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015 Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Zhang, Jinglu;  Han, Run;  Chen, Weijie;  Zhang, Weixiang;  Li, Ying;  Ji, Yuanhui;  Chen, Lijiang;  Pan, Hao;  Yang, Xinggang;  Pan, Weisan;  Ouyang, Defang
Favorite |  | TC[WOS]:13 TC[Scopus]:13 | Submit date:2018/10/30
Solid Dispersion  Big Data  Literature  Patent  Scientific Knowledge Mapping  Citespace  
Investigating the molecular dissolution process of binary solid dispersions by molecular dynamics simulations Journal article
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 13,Issue: 3,Page: 248-254
Authors:  Chan, TengIan;  Ouyang, Defang
Favorite |  | TC[WOS]:12 TC[Scopus]:14 | Submit date:2018/10/30
Solid Dispersion  Molecular Modeling  Dissolution Process  Ibuprofen  
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
View | Adobe PDF | Favorite |  | TC[WOS]:17 TC[Scopus]:19 | Submit date:2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design