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Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:13 TC[Scopus]:13 | Submit date:2021/03/01
Adipocytes  Adipose Tissue Inflammation  Autophagy  Cycloartane Triterpenoid  Il-1β, Macrophages  Macrophages  Nlrp3 Inflammasome  
SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 2
Authors:  Zhang,Tian;  Liu,Jingxin;  Tong,Qiang;  Lin,Ligen
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2021/03/01
Ampk  Chaperone-mediated Autophagy  Lipid Metabolism  Macroautophagy  Sirtuin 3  
SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions Journal article
Autophagy, 2019,Volume: 15,Issue: 8,Page: 1356-1375
Authors:  Kim,Tae Sung;  Jin,Yeung Bae;  Kim,Yi Sak;  Kim,Sup;  Kim,Jin Kyung;  Lee,Hye Mi;  Suh,Hyun Woo;  Choe,Jin Ho;  Kim,Young Jae;  Koo,Bon Sang;  Kim,Han Na;  Jung,Mingyu;  Lee,Sang Hee;  Kim,Don Kyu;  Chung,Chaeuk;  Son,Ji Woong;  Min,Jung Joon;  Kim,Jin Man;  Deng,Chu Xia;  Kim,Hyun Seok;  Lee,Sang Rae;  Jo,Eun Kyeong
Favorite |  | TC[WOS]:30 TC[Scopus]:30 | Submit date:2020/09/16
autophagy  mitochondrial homeostasis  Mycobacterium tuberculosis  PPARA  SIRT3  
SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity Journal article
Cell Death and Differentiation, 2019,Volume: 27,Issue: 1,Page: 329-344
Authors:  Zhang,Tian;  Liu,Jingxin;  Shen,Shengnan;  Tong,Qiang;  Ma,Xiaojun;  Lin,Ligen
Favorite |  | TC[WOS]:28 TC[Scopus]:26 | Submit date:2021/03/01
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3 Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 834,Page: 176-187
Authors:  Liu, Jing-Xin;  Shen, Sheng-Nan;  Tong, Qiang;  Wang, Yi-Tao;  Lin, Li-Gen
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2018/10/30
Honokiol  Oxidative Stress  Liver  Sirt3  Mitochondria  Fragmentation  
Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition Journal article
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 2018,Volume: 50,Issue: 2,Page: 131-142
Authors:  Chabi, Beatrice;  Fouret, Gilles;  Lecomte, Jerome;  Cortade, Fabienne;  Pessemesse, Laurence;  Baati, Narjes;  Coudray, Charles;  Lin, Ligen;  Tong, Qiang;  Wrutniak-Cabello, Chantal;  Casas, Francois;  Feillet-Coudray, Christine
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/10/30
Sirt3 isoforms  Mitochondria  Cardiolipin  Phospholipids  Skeletal muscle  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Fayang Zhou;  Anqi Wang;  Dan li;  Yitao Wang;  Ligen Lin
Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/10/31
Hepatic Stellate Cells  Liver Fibrosis  Penthorum Chinense Pursh  Pinocembrin  Silent Mating Type Information Regulation 2 Homolog 3  Sma- And Mad-related Proteins