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The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic Modification  Metabolic Landscape  Metabolomics  Obesity  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
Favorite |  | TC[WOS]:25 TC[Scopus]:29 | Submit date:2020/09/16
cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
Attenuation of Palmitic Acid–Induced Lipotoxicity by Chlorogenic Acid through Activation of SIRT1 in Hepatocytes Journal article
Molecular Nutrition and Food Research, 2019,Volume: 63,Issue: 14
Authors:  Yang,Lele;  Wei,Jinchao;  Sheng,Feiya;  Li,Peng
Favorite |  | TC[WOS]:10 TC[Scopus]:15 | Submit date:2021/03/01
Chlorogenic Acid  Lipotoxicity  Mitochondrial Dysfunction  Mitochondrial Fission/fusion  Saturated Free Fatty Acids  
Myricanol rescues dexamethasone-induced muscle dysfunction via a sirtuin 1-dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shen, SN;  Liao, QW;  Liu, JX;  Pan, RL;  Lee, SMY;  Lin, LG
Favorite |  | TC[WOS]:26 TC[Scopus]:23 | Submit date:2020/01/16
Autophagy  Myricanol  Sirt1  Dexamethasone  Muscle Atrophy  Pgc-1 Alpha  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
Authors:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
Favorite |  | TC[WOS]:32 TC[Scopus]:30 | Submit date:2019/01/15
Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review Journal article
Critical reviews in food science and nutrition, 2019,Volume: 59,Page: S116-S129
Authors:  Wang,Meng;  Ma,Li Juan;  Yang,Yan;  Xiao,Zeyu;  Wan,Jian Bo
Favorite |  | TC[WOS]:31 TC[Scopus]:29 | Submit date:2021/03/02
Alcoholic Liver Disease  Alcoholic Steatosis  Inflammation  Intestinal Homeostasis  N-3 Polyunsaturated Fatty Acids  Oxidative Stress  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor delta Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 139,Page: 384-394
Authors:  Wai San Cheang;  Wing Tak Wong;  Li Wang;  Chak Kwong Cheng;  Chi Wai Lau;  Ronald Chin Wan Ma;  Aimin Xu;  Nanping Wang;  Yu Huang;  Xiao Yu Tian
Favorite |  | TC[WOS]:32 TC[Scopus]:32 | Submit date:2020/04/09
Pparδ  Sirt1  Endothelial Dysfunction  Diet Induced Obesity  
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
ONCOGENE, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen, Tyler J.;  Kim, Seung-Jin;  Miao, Kai;  Huang, Zebin;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2018/10/30
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Chao;  Li, Chuwen;  Chen, Shenghui;  Li, Zhiping;  Ma, Lijuan;  Jia, Xuejing;  Wang, Kai;  Bao, Jiaolin;  Liang, Yeer;  Chen, Meiwan;  Li, Peng;  Su, Huanxing;  Lee, Simon Ming Yuen;  Liu, Kechun;  Wan, Jian-Bo;  He, Chengwei
Favorite |  | TC[WOS]:28 TC[Scopus]:46 | Submit date:2018/10/30