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Formation of Kiss1R/GPER Heterocomplexes Negatively Regulates Kiss1R-mediated Signalling through Limiting Receptor Cell Surface Expression Journal article
Journal of Molecular Biology, 2021,Volume: 433,Issue: 7
Authors:  Ke,Ran;  Lok,Samson Ian Sam;  Singh,Kailash;  Chow,Billy Kwok Chong;  Janovjak,Harald;  Lee,Leo Tsz On
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Cell Signaling  g Protein-coupled Estrogen Receptor  Gpcr Dimerization  Kisspeptin Receptor  
Validation of the 33-item Hypomania Checklist (HCL-33) in screening adolescents with bipolar disorder Journal article
Journal of Affective Disorders, 2021,Volume: 281,Page: 786-791
Authors:  Zhang,Yao;  Li,Wen;  Zhang,Wu Yang;  He,Fan;  Pan,Hong Ping;  Cheung,Teris;  Ungvari,Gabor S.;  Li,Shuying;  Xiang,Yu Tao;  Angst,Jules
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Adolescents  Bipolar disorder  HCL-33  Major depressive disorder  Validation  
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Oncogene, 2021,Volume: 40,Issue: 5,Page: 937-950
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen;  Shim,Joong Sup
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Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice Journal article
Acta Pharmacologica Sinica, 2021,Volume: 42,Issue: 2,Page: 199-208
Authors:  Wu,Man;  Lu,Guang;  Lao,Yuan zhi;  Zhang,Hong;  Zheng,Dan;  Zheng,Zhao qing;  Yi,Juan;  Xiang,Qian;  Wang,Li ming;  Tan,Hong sheng;  Zhou,Hua;  Shen,Han ming;  Xu,Hong xi
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garciesculenxanthone B  ischemia-reperfusion injury  mitophagy  Parkin  PINK1  
Boronate ester bond–based potentiometric aptasensor for screening carcinoembryonic antigen-glycoprotein using nanometer-sized CaCO3 with ion-selective electrode Journal article
Analytical and Bioanalytical Chemistry, 2021,Volume: 413,Issue: 4,Page: 1073-1080
Authors:  Chen,Ye;  Li,Bin;  Lyu,Peng;  Kwok,Hang Fai;  Ge,Lilin;  Wu,Qinan
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Aptasensor  Carcinoembryonic antigen  Ion-selective electrode  Nanometer-sized CaCO3  Potentiometric measurement  
Adsorbed hollow fiber immobilized tyrosinase for the screening of enzyme inhibitors from Pueraria lobata extract Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2021,Volume: 193
Authors:  Zhao,Cong Peng;  Yin,Shi Jun;  Chen,Guo Ying;  Wang,Yuan;  Chen,Hua;  Zhao,Jing;  Yang,Feng Qing
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Adsorbed hollow fibers  Enzyme immobilization  Inhibitor screening  Pueraria lobata  Tyrosinase  
Modeling Uremic Vasculopathy With Induced Pluripotent Stem Cell-Derived Endothelial Cells as a Drug Screening System Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 8
Authors:  Jang,Hye Ryoun;  Cho,Hyung Joon;  Zhou,Yang;  Shao,Ning Yi;  Lee,Kyungho;  Le,Hoai Huong Thi;  Jeon,Junseok;  Lee,Jung Eun;  Huh,Wooseong;  Ong,Sang Ging;  Lee,Won Hee;  Kim,Yoon Goo
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Chronic Kidney Disease  Endothelial Cells  Induced Pluripotent Stem Cells  Uremic Toxin  Uremic Vasculopathy  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
European Journal of Pharmaceutics and Biopharmaceutics, 2021,Volume: 158,Page: 336-346
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
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Dissolution profile  Machine learning  molecular dynamics (MD) simulations  Pharmacokinetic modeling  Solid dispersion  
Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
ACS Sensors, 2021
Authors:  Wu,Ke Jia;  Wu,Chun;  Chen,Feng;  Cheng,Sha Sha;  Ma,Dik Lung;  Leung,Chung Hang
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High-throughput screening  Iridium-based pH probe  Lysosomotropic compounds  Mitoxantrone  Time-resolved emission spectroscopy  
Fast Algorithm Based on Parallel Computing for Sample Entropy Calculation Journal article
IEEE Access, 2021
Authors:  Dong X.;  Chen C.;  Geng Q.;  Zhang W.;  Zhang X.D.
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Acceleration  Algorithm  Biomedical Monitoring  Entropy  Fast Computation  Graphics Processing Unit  Graphics Processing Units  Kernel  Parallel Computing  Sample Entropy  Standards  Time Series Analysis