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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Phenolic immunogenic cell death nanoinducer for sensitizing tumor to PD-1 checkpoint blockade immunotherapy Journal article
Biomaterials, 2021,Volume: 269
Authors:  Xie,Lisi;  Wang,Guohao;  Sang,Wei;  Li,Jie;  Zhang,Zhan;  Li,Wenxi;  Yan,Jie;  Zhao,Qi;  Dai,Yunlu
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Immunogenic Cell Death  Metal Phenolic Coordination  Pd-1 Immune Checkpoint Blockade Immunotherapy  Phenolic Nanoplatform  
Aqueous Extract of Salvia miltiorrhiza Bunge-Radix Puerariae Herb Pair Attenuates Osteoporosis in Ovariectomized Rats Through Suppressing Osteoclast Differentiation Journal article
Frontiers in Pharmacology, 2021,Volume: 11
Authors:  Qin,Huan;  Zhao,Wenwen;  Jiao,Yang;  Zheng,Haoyi;  Zhang,Hao;  Jin,Jingyu;  Li,Qiu;  Chen,Xiuping;  Gao,Xia;  Han,Yantao
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autophagy  osteoclast differentiation  osteoporosis  oxidative stress  Salvia miltiorrhiza bunge-radix puerariae  
Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity Journal article
Redox Biology, 2021,Volume: 38
Authors:  Xu,Jian;  Wang,Liming;  Zhang,Lihuan;  Zheng,Fang;  Wang,Fang;  Leng,Jianhang;  Wang,Keyi;  Héroux,Paul;  Shen,Han Ming;  Wu,Yihua;  Xia,Dajing
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Cell death  Cytotoxicity  MEHP  Mitochondrial ROS  PINK1-Parkin-mediated mitophagy  
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
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IFN-γ  Licochalcone A  Natural products  PD-L1  Protein synthesis inhibitor  ROS  
Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Gao,Cheng;  Huang,Qiaoxian;  Liu,Conghui;  Kwong,Cheryl H.T.;  Yue,Ludan;  Wan,Jian Bo;  Lee,Simon M.Y.;  Wang,Ruibing
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ROS-initiated chemiluminescence-driven payload release from macrocycle-based Azo-containing polymer nanocapsules Journal article
Journal of Materials Chemistry B, 2020,Volume: 8,Issue: 38,Page: 8878-8883
Authors:  Sun,Chen;  Wang,Ziyi;  Yue,Ludan;  Huang,Qiaoxian;  Lu,Siyu;  Wang,Ruibing
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NIR II-excited and ph-responsive ultrasmall nanoplatform for deep optical tissue and drug delivery penetration and effective cancer chemophototherapy Journal article
Molecular Pharmaceutics, 2020,Volume: 17,Issue: 10,Page: 3720-3729
Authors:  Zhao,Qi;  Zhu,Lipeng;  Gao,Duyang;  Xie,Lisi;  Dai,Yunlu
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Chemophototherapy  Drug Delivery Penetration  Optical Tissue Penetration  Photothermal Imaging  Ultrasmall Cus Nanoparticles  
Bilirubin Nanomedicines for the Treatment of Reactive Oxygen Species (ROS)-Mediated Diseases Journal article
Molecular Pharmaceutics, 2020,Volume: 17,Issue: 7,Page: 2260-2274
Authors:  Chen,Zhejie;  Vong,Chi Teng;  Gao,Caifang;  Chen,Shiyun;  Wu,Xu;  Wang,Shengpeng;  Wang,Yitao
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Bilirubin  Cancer  Inflammation  Nanoparticle  Ros  
Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy Journal article
Biomaterials, 2020,Volume: 246
Authors:  Yang,Yu;  Zhu,Wenjun;  Cheng,Liang;  Cai,Ren;  Yi,Xuan;  He,Jiaxuan;  Pan,Xiaoshu;  Yang,Lu;  Yang,Kai;  Liu,Zhuang;  Tan,Weihong;  Chen,Meiwan
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2021/03/01
Aptamer-drug conjugates (ApDCs)  Deep tumor penetration  Photodynamic therapy (PDT)  Tumor microenvironment (TME)