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Formation of Kiss1R/GPER Heterocomplexes Negatively Regulates Kiss1R-mediated Signalling through Limiting Receptor Cell Surface Expression Journal article
Journal of Molecular Biology, 2021,Volume: 433,Issue: 7
Authors:  Ke,Ran;  Lok,Samson Ian Sam;  Singh,Kailash;  Chow,Billy Kwok Chong;  Janovjak,Harald;  Lee,Leo Tsz On
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Cell Signaling  g Protein-coupled Estrogen Receptor  Gpcr Dimerization  Kisspeptin Receptor  
Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
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drug discovery  malignant melanoma  pan-RAF  S100B-p53 interaction  synergistic  
Cross-species recognition of SARS-CoV-2 to bat ACE2 Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2021,Volume: 118,Issue: 1
Authors:  Liu,Kefang;  Tan,Shuguang;  Niu,Sheng;  Wang,Jia;  Wu,Lili;  Sun,Huan;  Zhang,Yanfang;  Pan,Xiaoqian;  Qu,Xiao;  Du,Pei;  Meng,Yumin;  Jia,Yunfei;  Chen,Qian;  Deng,Chuxia;  Yan,Jinghua;  Wang,Hong Wei;  Wang,Qihui;  Qi,Jianxun;  Gao,George Fu
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ACE2  COVID-19  RBD  Rhinolophus macrotis  SARS-CoV-2  
LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 1
Authors:  Xiong,Minmin;  Wu,Mengshi;  Dan Peng,;  Huang,Weijun;  Chen,Zehong;  Ke,Haoxian;  Chen,Zewen;  Song,Wu;  Zhao,Yonghua;  Xiang,Andy P.;  Zhong,Xiaomin
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Dissecting the mechanism of Yuzhi Zhixue granule on ovulatory dysfunctional uterine bleeding by network pharmacology and molecular docking Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Li,Jialin;  Luo,Hua;  Liu,Xinkui;  Zhang,Jingyuan;  Zhou,Wei;  Guo,Siyu;  Chen,Xiuping;  Liu,Yingying;  Jia,Shanshan;  Wang,Haojia;  Li,Bingbing;  Cheng,Guoliang;  Wu,Jiarui
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Mechanisms  Molecular Docking  Network pharmacology  Ovulatory Dysfunctional Uterine Bleeding  Yuzhi zhixue granule  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
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BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons Journal article
Frontiers in Genetics, 2020,Volume: 11
Authors:  Lin,Jianing;  Huang,Pian;  Chen,Weineng;  Ye,Chenghui;  Su,Huanxing;  Yao,Xiaoli
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bioinformatics analysis  FN1 gene  gene expression profiles  motor neurons  sporadic amyotrophic lateral sclerosis  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
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8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
LncRNA UCA1 maintains the low-tumorigenic and nonmetastatic status by stabilizing E-cadherin in primary prostate cancer cells Journal article
Molecular Carcinogenesis, 2020,Volume: 59,Issue: 10,Page: 1174-1187
Authors:  Zhao,Xian;  Wang,Yanli;  He,Jianfeng;  Deng,Rong;  Huang,Xiaojun;  Guo,Yanmin;  Li,Lian;  Xie,Ruiyu;  Yu,Jianxiu
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E-cadherin  LncRNA UCA1  MDM2  miR-296-3p  primary prostate cancer cells  
Interfering with S100B–effector protein interactions for cancer therapy Journal article
Drug Discovery Today, 2020,Volume: 25,Issue: 9,Page: 1754-1761
Authors:  Wu,Ke Jia;  Wang,Wanhe;  Wang,Hui Min David;  Leung,Chung Hang;  Ma,Dik Lung
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