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Polysaccharides from mulberry (Morus alba L.) leaf prevents obesity by inhibiting pancreatic lipase in high-fat diet induced mice Journal article
International Journal of Biological Macromolecules, 2021,Volume: 192,Page: 452-460
Authors:  Li, Ruilin;  Xue, Zihan;  Jia, Yanan;  Wang, Yajie;  Li, Shuqin;  Zhou, Jingna;  Liu, Junyu;  Zhang, Min;  He, Chengwei;  Chen, Haixia
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Interaction mechanism  Mulberry leaf polysaccharides  Pancreatic lipase  
A combined network pharmacology and molecular biology approach to investigate the active ingredients and potential mechanisms of mulberry (Morus alba L.) leaf on obesity Journal article
Phytomedicine, 2021,Volume: 92
Authors:  Li, Ruilin;  Wang, Chunli;  Chen, Yue;  Li, Nannan;  Wang, Qirou;  Zhang, Min;  He, Chengwei;  Chen, Haixia
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hypolipidemic  mulberry leaf  network pharmacology  obesity  PI3K/Akt/Bcl-xl signaling pathways  
Hederagenin Protects PC12 Cells Against Corticosterone-Induced Injury by the Activation of the PI3K/AKT Pathway Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Lin, Ruohong;  Liu, Linlin;  Silva, Marta;  Fang, Jiankang;  Zhou, Zhiwei;  Wang, Haitao;  Xu, Jiangping;  Li, Tiejun;  Zheng, Wenhua
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Akt  corticosterone  depression  hederagenin  pathway  PC12 cells  PI3K  
Artemether confers neuroprotection on cerebral ischemic injury through stimulation of the Erk1/2-P90rsk-CREB signaling pathway Journal article
Redox Biology, 2021,Volume: 46
Authors:  Li, Shuai;  Peng, Tangming;  Zhao, Xia;  Silva, Marta;  Liu, Linlin;  Zhou, Wenshu;  Chen, Ligang;  Zheng, Wenhua
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Apoptosis  Artemether  Erk1/2-P90rsk-CREB  MCAO model  OGD/RP  ROS  
Current status and future perspectives on therapeutic potential of apigenin: Focus on metabolic-syndrome-dependent organ dysfunction Journal article
Antioxidants, 2021,Volume: 10,Issue: 10
Authors:  Alam, Waqas;  Rocca, Carmine;  Khan, Haroon;  Hussain, Yaseen;  Aschner, Michael;  De Bartolo, Anna;  Amodio, Nicola;  Angelone, Tommaso;  Cheang, Wai San
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Antioxidants  Apigenin  Flavonoids  Intracellular signalling  Metabolic syndrome  
β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Wu, Jiazhen;  Gan, Yuxuan;  Luo, Huijuan;  Xu, Nan;  Chen, Liping;  Li, Mengyao;  Guan, Fengkun;  Su, Ziren;  Lin, Zhixiu;  Xie, Jianhui;  Liu, Yuhong
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5-fluorouracil  cAMP/PKA/CREB pathway  intestinal mucositis  water transport  β-patchoulene  
Mechanisms of Gegen Qinlian Pill to ameliorate irinotecan-induced diarrhea investigated by the combination of serum pharmacochemistry and network pharmacology Journal article
Journal of Ethnopharmacology, 2021,Volume: 276
Authors:  Wu, Yihan;  Cheng, Yanfen;  Yang, Yuhan;  Wang, Di;  Yang, Xiaoqin;  Fu, Chaomei;  Zhang, Jinming;  Hu, Yichen
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CPT-11  Diarrhea  Gegen qinlian pill  Gut toxicity  Mechanisms of action  Network pharmacology  
Radix Astragali polysaccharide RAP directly protects hematopoietic stem cells from chemotherapy-induced myelosuppression by increasing FOS expression Journal article
International Journal of Biological Macromolecules, 2021,Volume: 183,Page: 1715-1722
Authors:  Bao, Wanrong;  Zhang, Quanwei;  Zheng, Hongming;  Li, Lifeng;  Liu, Man;  Cheng, Huiyuan;  Wong, Tinlong;  Zhang, Ge;  Lu, Aiping;  Bian, Zhaoxiang;  Ma, Diklung;  Leung, Chunghang;  Han, Quanbin
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Astragalus polysaccharide  FOS  Hematopoietic stem cell  Myelosuppression  Protective effect  
Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Jing, Mei;  Cen, Yun;  Gao, Fangfang;  Wang, Ting;  Jiang, Jinxin;  Jian, Qianqian;  Wu, Liangmiao;  Guo, Baojian;  Luo, Fangcheng;  Zhang, Gaoxiao;  Wang, Ying;  Xu, Lipeng;  Zhang, Zaijun;  Sun, Yewei;  Wang, Yuqiang
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diabetic kidney disease  metabolic abnormalities  mitochondrial function  nephroprotection  oxidative stress  
Engineering a Hydrogen-Sulfide-Based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy Journal article
Advanced Materials, 2021,Volume: 33,Issue: 22
Authors:  Li, Jie;  Xie, Lisi;  Li, Bei;  Yin, Chao;  Wang, Guohao;  Sang, Wei;  Li, Wenxi;  Tian, Hao;  Zhang, Zhan;  Zhang, Xuanjun;  Fan, Quli;  Dai, Yunlu
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anti-inflammation  hydrogen sulfide  hyperactive immunity  NIR-II fluorescence  photothermal therapy