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Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
IFN-γ  Licochalcone A  Natural products  PD-L1  Protein synthesis inhibitor  ROS  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai;  Kwok,Hang Fai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Embryonic stem cell  Peptide modification  Pluripotency  Self-renewal  Venom peptide  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2020/09/16
Atm-ampk-drp1  Brca1  Inflammasomes  Mitochondrial Dynamics  Mitophagy  
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2021/03/01
Antiangiogenesis  Apoptosis  Dietary compound  Glycyrrhetinic acid  Ovarian cancer  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai;  Zhang,Qing Wen;  Yang,Anping;  Liu,Fang
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Apoptosis  Liver cancer  Migration  Ophiorrhiza pumila  Proliferation  
Cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells Journal article
Natural Product Research, 2020
Authors:  Huang,Xiao Bin;  Yuan,Luo Wei;  Shao,Jing;  Yang,Yan;  Liu,Yi;  Lu,Jin Jian;  Chen,Lei
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
apoptosis  cancer  cytotoxicity  flavonoids  Sophora flavescens  
Cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells Journal article
Natural Product Research, 2020
Authors:  Huang,Xiao Bin;  Yuan,Luo Wei;  Shao,Jing;  Yang,Yan;  Liu,Yi;  Lu,Jin Jian;  Chen,Lei
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
apoptosis  cancer  cytotoxicity  flavonoids  Sophora flavescens