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Small Molecular Prodrug Amphiphile Self-Assembled AIE Dots for Cancer Theranostics Journal article
Frontiers in Bioengineering and Biotechnology, 2020,Volume: 8
Authors:  Yang,Xing;  Luo,Yuan;  Li,Sanpeng;  Xu,Xiuli;  Bao,Yingxia;  Yang,Jiaming;  Ouyang,Defang;  Fan,Xingxing;  Gong,Ping;  Cai,Lintao
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
AIE  cancer  prodrug  self-assembly  theranostics  
pH-Responsive supramolecular DOX-dimer based on cucurbit[8]uril for selective drug release Journal article
Chinese Chemical Letters, 2020,Volume: 31,Issue: 5,Page: 1235-1238
Authors:  Cheng,Qian;  Li,Shengke;  Ma,Yanlong;  Yin,Hang;  Wang,Ruibing
Favorite |  | TC[WOS]:8 TC[Scopus]:7 | Submit date:2021/03/02
Cucurbit[8]uril  Drug delivery  Host-guest  pH-Responsive  Prodrug  
ROS-Responsive Berberine Polymeric Micelles Effectively Suppressed the Inflammation of Rheumatoid Arthritis by Targeting Mitochondria Journal article
Nano-Micro Letters, 2020,Volume: 12,Issue: 1
Authors:  Fan,Xing xing;  Xu,Meng ze;  Leung,Elaine Lai Han;  Jun,Cai;  Yuan,Zhen;  Liu,Liang
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/04
Berberine  Nanoparticles  Oxygen Consumption Rate  Reactive Oxygen Species  Rheumatoid Arthritis  
Helix Self-Assembly Behavior of Amino Acid-Modified Camptothecin Prodrugs and Its Antitumor Effect Journal article
ACS Applied Materials and Interfaces, 2020,Volume: 12,Issue: 6,Page: 7466-7476
Authors:  Guo,Zhaopei;  Lin,Lin;  Hao,Kai;  Wang,Dianwei;  Liu,Feng;  Sun,Pingjie;  Yu,Haiyang;  Tang,Zhaohui;  Chen,Meiwan;  Tian,Huayu;  Chen,Xuesi
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
antitumor  camptothecin  prodrug  self-aggregate  π-πstack  
The novel platinum(IV) prodrug with self-assembly property and structure-transformable character against triple-negative breast cancer Journal article
Biomaterials, 2020,Volume: 232
Authors:  Yang,Conglian;  Tu,Kun;  Gao,Hanlu;  Zhang,Liao;  Sun,Yu;  Yang,Ting;  Kong,Li;  Ouyang,Defang;  Zhang,Zhiping
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/02
Adjudin  Drug resistance  Platinum(IV) prodrug  Self-assembly  Structure transform  Triple-negative breast cancer  
ROS directly activates transforming growth factor β type 1 receptor signalling in human vascular smooth muscle cells Journal article
Biochimica et Biophysica Acta - General Subjects, 2020,Volume: 1864,Issue: 1
Authors:  Mohamed,Raafat;  Cao,Yingnan;  Afroz,Rizwana;  Xu,Suowen;  Ta,Hang T.;  Barras,Michael;  Zheng,Wenhua;  Little,Peter J.;  Kamato,Danielle
Favorite |  | TC[WOS]:4 TC[Scopus]:6 | Submit date:2021/03/04
Apocynin  NADPH oxidase  Reactive oxygen species  Smad2 carboxy terminal  Smooth muscle cells  Transforming growth factor β type 1 receptor  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Investigational hypoxia-activated prodrugs: Making sense of future development Journal article
Current Drug Targets, 2019,Volume: 20,Issue: 6,Page: 668-678
Authors:  Su,Min Xia;  Zhang,Le Le;  Huang,Zhang Jian;  Shi,Jia Jie;  Lu,Jin Jian
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/02
Dna Alkylating Agents  Hypoxia-activated Prodrug  Patient Selection  Reductase Activity  Targeted Drugs  Topoisomerase Ii Inhibitors  
Tumour microenvironment-responsive semiconducting polymer-based self-assembling nanotheranostics Journal article
Nanoscale Horizons, 2019
Authors:  Zhen Yang;  Yunlu Dai;  Lingling Shan;  Zheyu Shen;  Zhantong Wang;  Bryant C. Yung;  Orit Jacobson;  Yijing Liu;  Wei Tang;  Sheng Wang;  Lisen Lin;  Gang Niu;  Pintong Huang;  Xiaoyuan Chen
Favorite |  | TC[WOS]:51 TC[Scopus]:28 | Submit date:2019/01/25
Hybrid Nanomedicine Fabricated from Photosensitizer-Terminated Metal-Organic Framework Nanoparticles for Photodynamic Therapy and Hypoxia-Activated Cascade Chemotherapy Journal article
SMALL, 2018,Volume: 15,Issue: 4
Authors:  Zhimei He;  Yunlu Dai;  Xiangli Li;  Dan Guo;  Yijing Liu;  Xiaolin Huang;  Jingjing Jiang;  Sheng Wang;  Guizhi Zhu;  Fuwu Zhang;  Lisen Lin;  Jun‐Jie Zhu;  Guocan Yu;  Xiaoyuan Chen
Favorite |  | TC[WOS]:57 TC[Scopus]:56 | Submit date:2020/05/13
Banoxantrone  Cascade Therapy  Hypoxia-activated Prodrugs  Nanoscale Metal-organic Frameworks  Photodynamic Therapy