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Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
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Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways Journal article
Journal of Ethnopharmacology, 2020,Volume: 261
Authors:  Li,Qiuping;  Wang,Guifang;  Xiong,Shi Hang;  Cao,Yuxue;  Liu,Baojun;  Sun,Jing;  Li,Lulu;  Mohammadtursun,Nabijan;  Yu,Hua;  Dong,Jingcheng;  Wu,Jinfeng
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Bu-shen-fang-chuan Formula (Bsfcf)  Copd  Inflammation  Nrf2  Pi3k/akt  
Mechanism Study of the Protective Effects of Sodium Tanshinone IIA Sulfonate Against Atorvastatin-Induced Cerebral Hemorrhage in Zebrafish: Transcriptome Analysis Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Zhou,Zhong Yan;  Zhao,Wai Rong;  Xiao,Ying;  Zhang,Jing;  Tang,Jing Yi;  Lee,Simon Ming Yuen
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atorvastatin  carbonic anhydrase  cerebral hemorrhage  hemoglobin  hypoxia-inducible factor 1  Na+/H+ exchanger  sodium tanshinone IIA sulfonate  traditional Chinese medicine  
Isolation and identification of antiarthritic constituents from glycine tabacina and network pharmacology-based prediction of their protective mechanisms against rheumatoid arthritis Journal article
Journal of Agricultural and Food Chemistry, 2020,Volume: 68,Issue: 39,Page: 10664-10677
Authors:  Tu,Yanbei;  Wang,Kai;  Jia,Xuejing;  Tan,Lihua;  Han,Bing;  Zhang,Qingwen;  Li,Yanfang;  He,Chengwei
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Coumestan  Glycine tabacina  Inflammation  Network pharmacology  Osteoclastogenesis  Rheumatoid arthritis  
Dolichosin A, a coumestan isolated from Glycine tabacina, inhibits IL-1β-induced inflammation in SW982 human synovial cells and suppresses RANKL-induced osteoclastogenesis: From network pharmacology to experimental pharmacology Journal article
Journal of Ethnopharmacology, 2020,Volume: 258
Authors:  Tu,Yanbei;  Wang,Kai;  Tan,Lihua;  Han,Bing;  Hu,Yuanjia;  Ding,Hang;  He,Chengwei
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Dolichosin A  Glycine tabacina (Labill.) benth  Inflammation  Network pharmacology  Osteoclastogenesis  Rheumatoid arthritis  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
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cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal article
Cell Reports, 2019,Volume: 29,Issue: 11,Page: 3374-3384.e5
Authors:  Yang,Yang;  Ren,Zhili;  Xu,Faxiang;  Meng,Ya;  Zhang,Yumeng;  Ai,Nana;  Long,Yan;  Fok,Hio Ian;  Deng,Chunhao;  Zhao,Xianyang;  Huang,Liancheng;  Zhao,Qi;  Wang,Jiaxian;  Liu,Weiwei;  Ge,Wei;  Chen,Guokai
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Cardiomyocyte  Casein Kinase Ii  Heterogeneity  Human Embryonic Stem Cells  Igf  Insulin  Mesoderm  Pi3k  Temporal Regulation  Wnt  
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
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App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells Journal article
STEM CELLS, 2019,Volume: 37,Issue: 8,Page: 1030-1041
Authors:  Carlos Godoy‐Parejo;  Chunhao Deng;  Weiwei Liu;  Guokai Chen
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2020/05/21
Hesc  Cell Survival  Cell Adhesion  Focal Adhesion  Niche  Individualization  Insulin  Integrin  Caspase  Igf  Akt  
Yinchenhao decoction suppresses rat liverfibrosis involved in an apoptosisregulation mechanism based on network pharmacology and transcriptomicanalysis Journal article
Biomedicine & Pharmacotherapy, 2019,Volume: 114
Authors:  Fei-Fei Cai;  Yan-Qin Bian;  Rong Wu;  Yang Sun;  Xiao-Le Chen;  Meng-Die Yang;  Qian-ru Zhang;  Yuanjia Hu;  Ming-Yu Sun;  Shi-Bing Su
Favorite |  | TC[WOS]:25 TC[Scopus]:23 | Submit date:2020/10/23
Yinchenhao Decoction  Liver Fibrosis  Network Pharmacology  Transcriptomics  Apoptosis