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Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
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IFN-γ  Licochalcone A  Natural products  PD-L1  Protein synthesis inhibitor  ROS  
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
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Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
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AD animal models  Alzheimer's disease  Clinical trials  EGCG  Neuroprotective effects  Systematic review  
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Lyu,Junfang;  Yang,Eun Ju;  Zhang,Baoyuan;  Wu,Changjie;  Pardeshi,Lakhansing;  Shi,Changxiang;  Mou,Pui Kei;  Liu,Yifan;  Tan,Kaeling;  Shim,Joong Sup
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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
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Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
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Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
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Post-translational modifications of PRC2: signals directing its activity Journal article
Epigenetics and Chromatin, 2020,Volume: 13,Issue: 1
Authors:  Yang,Yiqi;  Li,Gang
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Cgis  Cis Chromatin Features  Facultative Subunits  Methylation  Phosphorylation  Prc2  Ptms  Ubiquitination  
Structure-guided discovery of a luminescent theranostic toolkit for living cancer cells and the imaging behavior effect Journal article
Chemical Science, 2020,Volume: 11,Issue: 42,Page: 11404-11412
Authors:  Wu,Chun;  Wu,Ke Jia;  Liu,Jin Biao;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
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Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
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Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase