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Tracking evidences of Coptis chinensis for the treatment of inflammatory bowel disease from pharmacological, pharmacokinetic to clinical studies Journal article
Journal of Ethnopharmacology, 2021,Volume: 268
Authors:  Yang,Yuhan;  Vong,Chi Teng;  Zeng,Shan;  Gao,Caifang;  Chen,Zhejie;  Fu,Chaomei;  Wang,Shengpeng;  Zou,Liang;  Wang,Anqi;  Wang,Yitao
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Berberine  Clinical study  Coptis chinensis  Inflammatory bowel disease  Pharmacokinetics  Pharmacology  Review  
Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats Journal article
Journal of Ethnopharmacology, 2021,Volume: 265
Authors:  Yang,Ying;  Hu,Nan;  Gao,Xue Jiao;  Li,Ting;  Yan,Zhi Xiang;  Wang,Pan Pan;  Wei,Bin;  Li,Sai;  Zhang,Zai Jun;  Li,Song Lin;  Yan,Ru
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Cyclosporine A  Experimental colitis  Ginseng  Gut microbiota  Oral pharmacokinetics  Tight junction  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
European Journal of Pharmaceutics and Biopharmaceutics, 2021,Volume: 158,Page: 336-346
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
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Dissolution profile  Machine learning  molecular dynamics (MD) simulations  Pharmacokinetic modeling  Solid dispersion  
Development of a Highly Water-Soluble Lycopene Cyclodextrin Ternary Formulation by the Integrated Experimental and Modeling Techniques Journal article
AAPS PharmSciTech, 2021,Volume: 22,Issue: 1
Authors:  Ma,Yan;  Zhong,Liuting;  Peng,Zhuo;  Liu,Xinyang;  Ouyang,Defang;  Guan,Shixia
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bioavailability  hot-melt extrusion  lycopene  molecular dynamics simulation  ternary formulation  
Pharmacological review of isobavachalcone, a naturally occurring chalcone Journal article
Pharmacological Research, 2021
Authors:  Wang,Miaojuan;  Lin,Ligen;  Lu,Jin Jian;  Chen,Xiuping
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Isobavachalcone  Molecular targets  Pharmacokinetic  Pharmacology  
NIR-II-Activated Yolk-Shell Nanostructures as an Intelligent Platform for Parkinsonian Therapy Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 10,Page: 6876-6887
Authors:  Liu,Yao;  Zhu,Daoming;  Luo,Jingshan;  Chen,Xiaojia;  Gao,Liqian;  Liu,Wei;  Chen,Tongkai
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blood-brain barrier  brain drug delivery  gold nanorods  mesoporous silica  neurodegenerative disorders  NIR-II biowindow  
Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Bian,Yaqi;  Zhao,Chen;  Lee,Simon Ming Yuen
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anti-depressant effect  anxiolytic effect  neuroprotective effects  saffron  saffron constituents  traditional Chinese medicine  
A pharmacological review of dicoumarol: An old natural anticoagulant agent Journal article
Pharmacological Research, 2020,Volume: 160
Authors:  Sun,Chong;  Zhao,Wenwen;  Wang,Xumei;  Sun,Yinxiang;  Chen,Xiuping
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Bioactivity  Dicoumarol  Pharmacokinetic  Side effects  
Size effect of curcumin nanocrystals on dissolution, airway mucosa penetration, lung tissue distribution and absorption by pulmonary delivery Journal article
Colloids and Surfaces B: Biointerfaces, 2020,Volume: 186
Authors:  He,Yuan;  Liang,Yingmin;  Mak,Judith Choi Wo;  Liao,Yonghong;  Li,Ting;  Yan,Ru;  Li,Hai Feng;  Zheng,Ying
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Förster resonance energy transfer (FRET)  Lung absorption  Nanocrystals  Pulmonary delivery  Size effect  
Polylysine and cysteine functionalized chitosan nanoparticle as an efficient platform for oral delivery of paclitaxel Journal article
Carbohydrate Polymers, 2020,Volume: 229
Authors:  Du,Xiao;  Yin,Shaoping;  Xu,Linqiang;  Ma,Jiqun;  Yu,Hua;  Wang,Guangji;  Li,Juan
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Bioavailability  Chitosan  Mucoadhesion  Nanoparticle  Oral delivery