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A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway Journal article
Computational and Structural Biotechnology Journal, 2021,Volume: 19,Page: 2664-2675
Authors:  Wei, Ran;  Wu, Qiushuang;  Ai, Nana;  Wang, Lei;  Zhou, Mei;  Shaw, Chris;  Chen, Tianbao;  Ye, Richard Dequan;  Ge, Wei;  Siu, Shirley W.I.;  Kwok, Hang Fai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Anti-angiogenesis  Chromogranin a  Vasostatin-1  Vegfr2  
Mass production of active recombinant Chryseobacterium proteolyticum protein glutaminase in Escherichia coli using a sequential dual expression system and one-step purification Journal article
IUBMB Life, 2020,Volume: 72,Issue: 11,Page: 2391-2399
Authors:  Lu,Xin;  Poon,Terence Chuen Wai;  Zhang,Hongmin
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
biochemical engineering  enzyme engineering  gene expression  protein purification  protein stability  
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from the Skin Secretion of Odorrana schmackeri Journal article
Toxins, 2020,Volume: 12,Issue: 8
Authors:  Zhou,Xiaowei;  Liu,Yue;  Gao,Yitian;  Wang,Yuanxing;  Xia,Qiang;  Zhong,Ruimin;  Ma,Chengbang;  Zhou,Mei;  Xi,Xinping;  Shaw,Chris;  Chen,Tianbao;  Wu,Di;  Kwok,Hang Fai;  Wang,Lei
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/04
Antimicrobial activity  Skin-derived peptides  Stability  Waxworm model  
Clinical and Recent Patents Applications of PD-1/PD-L1 Targeting Immunotherapy in Cancer Treatment—Current Progress, Strategy, and Future Perspective Journal article
Frontiers in Immunology, 2020,Volume: 11
Authors:  Guo,Libin;  Wei,Ran;  Lin,Yao;  Kwok,Hang Fai
Favorite |  | TC[WOS]:10 TC[Scopus]:12 | Submit date:2021/03/04
clinical trial  immunotherapy  patent  PD-1  PD-L1  
Pharmacological effects of a novel bradykinin-related peptide (RR-18) from the skin secretion of the hejiang frog (Ordorrana hejiangensis) on smooth muscle Journal article
Biomedicines, 2020,Volume: 8,Issue: 7
Authors:  Zhou,Xiaowei;  Xu,Jie;  Zhong,Ruimin;  Ma,Chengbang;  Zhou,Mei;  Cao,Zhijian;  Xi,Xinping;  Shaw,Chris;  Chen,Tianbao;  Wang,Lei;  Kwok,Hang Fai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Antagonist  Bradykinin related peptide  Frog  Skin secretion  Smooth muscle  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai;  Kwok,Hang Fai
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/04
Embryonic stem cell  Peptide modification  Pluripotency  Self-renewal  Venom peptide  
Deep-AmPEP30: Improve Short Antimicrobial Peptides Prediction with Deep Learning Journal article
Molecular Therapy - Nucleic Acids, 2020,Volume: 20,Page: 882-894
Authors:  Yan,Jielu;  Bhadra,Pratiti;  Li,Ang;  Sethiya,Pooja;  Qin,Longguang;  Tai,Hio Kuan;  Wong,Koon Ho;  Siu,Shirley W.I.
Favorite |  | TC[WOS]:20 TC[Scopus]:22 | Submit date:2021/03/04
AmPEP  ampicillin  antimicrobial peptide  AxPEP  Candida glabrata  convolutional neural network  drug discovery  machine learning  reduced amino acid composition  
Simultaneously quantitative analysis of peptides and chemical components in Cervus and Cucumis polypeptide injection (Songmeile®) using reversed phase liquid chromatography-hydrophilic interaction liquid chromatography–tandem mass spectrometry Journal article
Journal of Chromatography A, 2020,Volume: 1617
Authors:  Liu, Wenjing;  Cao, Yan;  Ren, Yi;  Xu, Xia;  He, Liqun;  Xia, Ruixue;  Tu, Pengfei;  Wang, Yitao;  Song, Yuelin;  Li, Jun
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/09/13
Cervus And Cucumis Polypeptide Injection  Multiply Charged Ion transitIons  Online Energy-resolved Mass Spectrometry  Peptides  Reversed Phase Liquid Chromatography-hydrophilic Interaction Liquid Chromatography  
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Molecular Therapy - Oncolytics, 2020,Volume: 16,Page: 7-19
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.;  Kwok,Hang Fai
Favorite |  | TC[WOS]:14 TC[Scopus]:13 | Submit date:2021/03/04
angiogenesis  anticancer peptides  antimicrobial peptides  apoptosis  drug discovery and development  molecular dynamics  targeted therapy  
Enhanced Fluorescence for Bioassembly by Environment-Switching Doping of Metal Ions Journal article
Advanced Functional Materials, 2020,Volume: 30,Issue: 10
Authors:  Kai Tao;  Yu Chen;  Asuka A. Orr;  Zhen Tian;  Pandeeswar Makam;  Sharon Gilead;  Mingsu Si;  Sigal Rencus-Lazar;  Songnan Qu;  Mingjun Zhang;  hanourios Tamamis;  Ehud Gazit
Favorite |  | TC[WOS]:10 TC[Scopus]:13 | Submit date:2021/03/09
Aromatic Cyclodipeptides  Bioinspired Leds  Metal Ion Doping  Supramolecular Fluorescence  Very Initial Oligomerization