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Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
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B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Molecular evidence of herbal formula: a network-based analysis of Si-Wu decoction Journal article
Phytochemical Analysis, 2021,Volume: 32,Issue: 2,Page: 198-205
Authors:  Zuo,Hua Li;  Zhang,Qian Ru;  Chen,Cen;  Yang,Feng Qing;  Yu,Hua;  Hu,Yuan Jia
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Network Module  Network Pharmacology  Neuroendocrine Immunomodulation  Phytochemical Information  Si-wu Decoction  
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
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Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Dihydrotanshinone i Attenuates Plaque Vulnerability in Apolipoprotein E-Deficient Mice: Role of Receptor-Interacting Protein 3 Journal article
Antioxidants and Redox Signaling, 2021,Volume: 34,Issue: 5,Page: 351-363
Authors:  Zhao,Wenwen;  Li,Chunxia;  Zhang,Hao;  Zhou,Qihui;  Chen,Xuehong;  Han,Yantao;  Chen,Xiuping
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ApoE-/-mice  RIP3  TLR4 dimerization  vulnerable  
Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice Journal article
Acta Pharmacologica Sinica, 2021,Volume: 42,Issue: 2,Page: 199-208
Authors:  Wu,Man;  Lu,Guang;  Lao,Yuan zhi;  Zhang,Hong;  Zheng,Dan;  Zheng,Zhao qing;  Yi,Juan;  Xiang,Qian;  Wang,Li ming;  Tan,Hong sheng;  Zhou,Hua;  Shen,Han ming;  Xu,Hong xi
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garciesculenxanthone B  ischemia-reperfusion injury  mitophagy  Parkin  PINK1  
Aqueous Extract of Salvia miltiorrhiza Bunge-Radix Puerariae Herb Pair Attenuates Osteoporosis in Ovariectomized Rats Through Suppressing Osteoclast Differentiation Journal article
Frontiers in Pharmacology, 2021,Volume: 11
Authors:  Qin,Huan;  Zhao,Wenwen;  Jiao,Yang;  Zheng,Haoyi;  Zhang,Hao;  Jin,Jingyu;  Li,Qiu;  Chen,Xiuping;  Gao,Xia;  Han,Yantao
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autophagy  osteoclast differentiation  osteoporosis  oxidative stress  Salvia miltiorrhiza bunge-radix puerariae  
Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 1
Authors:  Wang,Panpan;  Chen,Xi;  Wang,Yuanyuan;  Jia,Congcong;  Liu,Xinyao;  Wang,Ying;  Wu,Haifeng;  Cai,Huaibin;  Shen,Han Ming;  Le,Weidong
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Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity Journal article
Redox Biology, 2021,Volume: 38
Authors:  Xu,Jian;  Wang,Liming;  Zhang,Lihuan;  Zheng,Fang;  Wang,Fang;  Leng,Jianhang;  Wang,Keyi;  Héroux,Paul;  Shen,Han Ming;  Wu,Yihua;  Xia,Dajing
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Cell death  Cytotoxicity  MEHP  Mitochondrial ROS  PINK1-Parkin-mediated mitophagy  
TNF–TNFR2 signal plays a decisive role in the activation of CD4+Foxp3+ Regulatory T Cells: Implications in the Treatment of Autoimmune Diseases and Cancer Book chapter
出自: Advances in Experimental Medicine and Biology, 2021, 页码: 257-272
Authors:  Islam,Md Sahidul;  Yang,Yang;  Chen,Xin
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Autoimmune diseases  Cancer  CD4+Foxp3+ regulatory T cells  TNF  TNFR2  
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
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IFN-γ  Licochalcone A  Natural products  PD-L1  Protein synthesis inhibitor  ROS