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Quality of life in Parkinson's disease: A systematic review and meta-analysis of comparative studies Journal article
CNS Neuroscience and Therapeutics, 2021,Volume: 27,Issue: 3,Page: 270-279
Authors:  Zhao,Na;  Yang,Yuan;  Zhang,Ling;  Zhang,Qinge;  Balbuena,Lloyd;  Ungvari,Gabor S.;  Zang,Yu Feng;  Xiang,Yu Tao
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comparative study  meta-analysis  Parkinson's disease  quality of life  
Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity Journal article
Redox Biology, 2021,Volume: 38
Authors:  Xu,Jian;  Wang,Liming;  Zhang,Lihuan;  Zheng,Fang;  Wang,Fang;  Leng,Jianhang;  Wang,Keyi;  Héroux,Paul;  Shen,Han Ming;  Wu,Yihua;  Xia,Dajing
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Cell death  Cytotoxicity  MEHP  Mitochondrial ROS  PINK1-Parkin-mediated mitophagy  
Polymeric nanoparticles-based brain delivery with improved therapeutic efficacy of ginkgolide b in parkinson’s disease Journal article
International Journal of Nanomedicine, 2020,Volume: 15,Page: 10453-10467
Authors:  Zhao,Yuying;  Xiong,Sha;  Liu,Piaoxue;  Liu,Wei;  Wang,Qun;  Liu,Yao;  Tan,Hanxu;  Chen,Xiaojia;  Shi,Xuguang;  Wang,Qi;  Chen,Tongkai
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Blood–brain Barrier  Drug Delivery System  Endocytosis  Pd Treatment  Zebrafish  
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong,Sha;  Li,Zhongjun;  Liu,Yao;  Wang,Qun;  Luo,Jingshan;  Chen,Xiaojia;  Xie,Zhongjian;  Zhang,Yuan;  Zhang,Han;  Chen,Tongkai
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Black Phosphorus Nanosheets  Blood-brain Barrier  Brain Targeting  Drug Delivery  Lactoferrin  
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020,Volume: 1866,Issue: 10
Authors:  Shen,Linjing;  Wang,Changliang;  Chen,Liang;  Leung,Ka Lai;  Lo,Esther;  Lakso,Merja;  Wong,Garry
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C. Elegans  Lewy Body Dementia  Neurodegeneration  Parkinson's Disease  Tdp-1/tdp-43  Tdp-43  Α-synuclein  
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
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Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6 Journal article
Brain, Behavior, and Immunity, 2020,Volume: 88,Page: 640-653
Authors:  Han,Chaojun;  Yan,Pengju;  He,Tao;  Cheng,Junjie;  Zheng,Wenhua;  Zheng,Long Tai;  Zhen,Xuechu
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Dopaminergic neuron  Microglia  Neuroinflammation  NF-κB  PHLDA1  TRAF6  Ubiquitination  
Autophagy and parkinson’s disease Book chapter
出自: Advances in Experimental Medicine and Biology:Singapore: Springer Singapore, 2020, 页码: 21-51
Authors:  Lu,Jiahong;  Wu,Mingyue;  Yue,Zhenyu
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Autophagy  Parkinson Disease  Α-synuclein  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
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Degradation  Neuroprotection  Parkinson's Disease  Proteasome  Α-synuclein  
Highly stabilized nanocrystals delivering Ginkgolide B in protecting against the Parkinson's disease Journal article
International Journal of Pharmaceutics, 2020,Volume: 577
Authors:  Liu,Yao;  Liu,Wei;  Xiong,Sha;  Luo,Jingshan;  Li,Ye;  Zhao,Yuying;  Wang,Qun;  Zhang,Zexin;  Chen,Xiaojia;  Chen,Tongkai
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Blood-brain Barrier  Drug Delivery  Gastrointestinal Tract  Nanocrystals  Parkinson's Disease