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Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Drug Discovery  Malignant Melanoma  Pan-raf  S100b-p53 Interaction  Synergistic  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2021/03/02
The role of autophagy in liver cancer: Crosstalk in signaling pathways and potential therapeutic targets Journal article
Pharmaceuticals, 2020,Volume: 13,Issue: 12,Page: 1-27
Authors:  Cui,Jianzhou;  Shen,Han Ming;  Lim,Lina Hsiu Kim
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
AMPK  Autophagy  HCC  MAPK  MTOR  P53  ULK1  
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice Journal article
Environmental Pollution, 2020,Volume: 265
Authors:  Liu,Jianhui;  Li,Xiangyang;  Zhou,Guiqing;  Sang,Yujian;  Zhang,Yue;  Zhao,Yanzhi;  Ge,Wei;  Sun,Zhiwei;  Zhou,Xianqing
Favorite |  | TC[WOS]:5 TC[Scopus]:8 | Submit date:2021/03/02
Histone-to-protamine Exchange  L3mbtl2  P53 Apoptosis Pathway  Rnf8-ubh2a/ubh2b Pathway  Silica Nanoparticles  
Interfering with S100B–effector protein interactions for cancer therapy Journal article
Drug Discovery Today, 2020,Volume: 25,Issue: 9,Page: 1754-1761
Authors:  Wu,Ke Jia;  Wang,Wanhe;  Wang,Hui Min David;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/01
Anti-cancer effects of polyphenols via targeting p53 signaling pathway: updates and future directions Journal article
Biotechnology Advances, 2020,Volume: 38
Authors:  Khan,Haroon;  Reale,Marcella;  Ullah,Hammad;  Sureda,Antoni;  Tejada,Silvia;  Wang,Ying;  Zhang,Zhang Jin;  Xiao,Jianbo
Favorite |  | TC[WOS]:44 TC[Scopus]:43 | Submit date:2021/03/02
Anticancer  Chemoresistance  Clinical Perspectives  P53 Signaling Pathways  Polyphenols  
Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 4033-4039
Authors:  Tam,Benjamin;  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/02
Molecular Dynamic Simulation  Pathogenic  Protein structure  Ramachandran plot  TP53  Variant of Uncertain Significance  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 9
Authors:  Bao, WR;  Li, ZP;  Zhang, QW;  Li, LF;  Liu, HB;  Ma, DL;  Leung, CH;  Lu, AP;  Bian, Z;  Han, QB
Favorite |  | TC[WOS]:10 TC[Scopus]:9 | Submit date:2020/03/24
Cell Cycle  Astragalus Polysaccharide  Cytotoxicity  Protective Effect  Apoptosis