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Dihydrotanshinone i Attenuates Plaque Vulnerability in Apolipoprotein E-Deficient Mice: Role of Receptor-Interacting Protein 3 Journal article
Antioxidants and Redox Signaling, 2021,Volume: 34,Issue: 5,Page: 351-363
Authors:  Zhao,Wenwen;  Li,Chunxia;  Zhang,Hao;  Zhou,Qihui;  Chen,Xuehong;  Han,Yantao;  Chen,Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
ApoE-/-mice  RIP3  TLR4 dimerization  vulnerable  
Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds Journal article
Pharmacology and Therapeutics, 2020,Volume: 214
Authors:  Yu,Jie;  Zhong,Bingling;  Xiao,Qingwen;  Du,Lida;  Hou,Ying;  Sun,Hong Shuo;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
Cancer  Natural compounds  Programmed necrosis  
3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ Journal article
FASEB Journal, 2020,Volume: 34,Issue: 3,Page: 4369-4383
Authors:  Kang,Kidong;  Quan,Khong Trong;  Byun,Hee Sun;  Lee,So Ra;  Piao,Xuezhe;  Ju,Eunjin;  Park,Kyeong Ah;  Sohn,Kyung Cheol;  Shen,Han Ming;  Na,Min Kyun;  Hur,Gang Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
3AR-C  apoptosis  IKKβ  necroptosis  phosphorylation  RIPK1  TNF  
Induction of an MLKL mediated non-canonical necroptosis through reactive oxygen species by tanshinol A in lung cancer cells Journal article
Biochemical Pharmacology, 2020,Volume: 171
Authors:  Liu,Xin;  Zhang,Yiying;  Gao,Hongwei;  Hou,Ying;  Lu,Jin jian;  Feng,Yulin;  Xu,Qiongming;  Liu,Bo;  Chen,Xiuping
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
Lung cancer  MLKL  Programmed necrosis  ROS  Tanshinol A  
Inhibition of Lung Cancer by 2-Methoxy-6-Acetyl-7-Methyljuglone Through Induction of Necroptosis by Targeting Receptor-Interacting Protein 1 Journal article
Antioxidants and Redox Signaling, 2019,Volume: 31,Issue: 2,Page: 93-108
Authors:  Sun,Wen;  Yu,Jie;  Gao,Hongwei;  Wu,Xiaxia;  Wang,Sheng;  Hou,Ying;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:8 TC[Scopus]:10 | Submit date:2021/03/01
cancer  drug resistance  MAM  necroptosis  RIP1  
Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
Authors:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
Favorite |  | TC[WOS]:0 TC[Scopus]:10 | Submit date:2019/01/16
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Apoptosis, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao W.-X.;  Li T.;  Tang Z.-H.;  Zhang L.-L.;  Wang Z.-Y.;  Guo X.;  Su M.-X.;  Chen X.;  Lu J.-J.
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2018/12/28
Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang;  Xia Guo;  Min‑Xia Su;  Xiuping Chen;  Jin‑Jian Lu
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 344,Page: 35-45
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan;  Chen, Xiuping
Favorite |  | TC[WOS]:16 TC[Scopus]:15 | Submit date:2018/10/30
15,16-dihydrotanshinone i  Ulcerative Colitis  Inflammation  Necroptosis  
Oxidative stress induced both apoptosis and necroptosis in endothelial cells Conference paper
Authors:  Chen, Xiuping;  Zhao, Wenwen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30