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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2020/09/16
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng;  Zhang,Dali;  Huang,Junlan;  Luo,Fengtao;  Li,Fangfang;  Ni,Zhenhong;  Zhou,Siru;  Chen,Hangang;  Chen,Shuai;  Chen,Liang;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Liu,Peng;  Yin,Liangjun;  Qiu,Juhui;  Chen,Di;  Deng,Chuxia;  Xie,Yangli;  Luo,Lingfei;  Chen,Lin
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2020/09/16
Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo Journal article
Cancer Science, 2020,Volume: 111,Issue: 10,Page: 3564-3575
Authors:  Wang,Xingshun;  Feng,Weimin;  Peng,Cheng;  Chen,Shiyun;  Ji,Hongbin;  Zhong,Hanbing;  Ge,Wei;  Zhang,Yandong
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/02
DHX33  lung cancer  oncogene  Ras  RNA helicase  
Genomic characteristics and drug screening among organoids derived from non-small cell lung cancer patients Journal article
Thoracic Cancer, 2020,Volume: 11,Issue: 8,Page: 2279-2290
Authors:  Chen,Jing Hua;  Chu,Xiang Peng;  Zhang,Jia Tao;  Nie,Qiang;  Tang,Wen Fang;  Su,Jian;  Yan,Hong Hong;  Zheng,Hong Ping;  Chen,Ze Xin;  Chen,Xin;  Song,Meng Meng;  Yi,Xin;  Li,Pan Song;  Guan,Yan Fang;  Li,Gang;  Deng,Chu Xia;  Rosell,Rafael;  Wu,Yi Long;  Zhong,Wen Zhao
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/02
Consistency analysis  drug screening  non-small cell lung cancer  patient-derived organoid  whole exome sequencing  
Current strategies for treating NSCLC: From biological mechanisms to clinical treatment Journal article
Cancers, 2020,Volume: 12,Issue: 6,Page: 1-24
Authors:  Li,Junnan;  Kwok,Hang Fai
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2021/03/04
Combination targeted therapy  Drug resistance mechanism  EGFR mutation  Lung cancer  
Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling Journal article
Cell Death and Disease, 2020,Volume: 11,Issue: 2
Authors:  Ke,Minjing;  Chong,Cheong Meng;  Zeng,Haitao;  Huang,Miaodan;  Huang,Zhijian;  Zhang,Ke;  Cen,Xiaotong;  Lu,Jia Hong;  Yao,Xiaoli;  Qin,Dajiang;  Su,Huanxing
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/01
Autophagy and parkinson’s disease Book chapter
出自: Advances in Experimental Medicine and Biology, 2020, 页码: 21-51
Authors:  Lu,Jiahong;  Wu,Mingyue;  Yue,Zhenyu
Favorite |  | TC[WOS]:5 TC[Scopus]:3 | Submit date:2021/03/02
Autophagy  Parkinson disease  α-synuclein  
Variants of DNA mismatch repair genes derived from 33,998 Chinese individuals with and without cancer reveal their highly ethnic-specific nature Journal article
European Journal of Cancer, 2020,Volume: 125,Page: 12-21
Authors:  Zhang,Li;  Bhaskaran,Shanmuga Priya;  Huang,Teng;  Dong,Hui;  Chandratre,Khyati;  Wu,Xiaobing;  Qin,Zixin;  Wang,Xiaoyu;  Cao,Wenming;  Chen,Tianhui;  Lynch,Henry;  Wang,San Ming
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/02
Cancer  Chinese  Classification  Ethnicity  MMR genes  Mutation  
Disruption of dmrt1 rescues the all-male phenotype of the cyp19a1a mutant in zebrafish - A novel insight into the roles of aromatase/estrogens in gonadal differentiation and early folliculogenesis Journal article
Development (Cambridge), 2020,Volume: 147,Issue: 4
Authors:  Wu,Kun;  Song,Weiyi;  Zhang,Zhiwei;  Ge,Wei
Favorite |  | TC[WOS]:9 TC[Scopus]:13 | Submit date:2021/03/02
Aromatase  Cyp19a1a  Dmrt1  Folliculogenesis  Sex differentiation  Zebrafish  
Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 723-736
Authors:  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:7 TC[Scopus]:9 | Submit date:2021/03/02
BRCA1  BRCT  Molecular dynamics simulation  PCA  Unclassified variants  VUS