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Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Co-expression network analysis of lncrnas and mrnas in rat liver tissue reveals the complex interactions in response to pathogenic cytotoxicity Journal article
International Journal of Biological Sciences, 2019,Volume: 15,Issue: 11,Page: 2296-2307
Authors:  Leng D.;  Huang C.;  Lei K.C.;  Sun S.;  Sun B.;  Zhang X.D.
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Cytotoxicity  Interaction Network  Liver Disease  Lncrnas  
Re-analysis of the coral Acropora digitifera transcriptome reveals a complex lncRNAs-mRNAs interaction network implicated in Symbiodinium infection Journal article
BMC Genomics, 2019,Volume: 20,Issue: 1
Authors:  Huang C.;  Leng D.;  Sun S.;  Zhang X.D.
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Acropora Digitifera  Alternative Splicing  Deep Rna-sequencing  Long Non-coding Rnas  Symbiodinium  Transcriptome  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
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cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:9 TC[Scopus]:8 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition Journal article
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 2018,Volume: 50,Issue: 2,Page: 131-142
Authors:  Chabi, Beatrice;  Fouret, Gilles;  Lecomte, Jerome;  Cortade, Fabienne;  Pessemesse, Laurence;  Baati, Narjes;  Coudray, Charles;  Lin, Ligen;  Tong, Qiang;  Wrutniak-Cabello, Chantal;  Casas, Francois;  Feillet-Coudray, Christine
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Sirt3 isoforms  Mitochondria  Cardiolipin  Phospholipids  Skeletal muscle  
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 93-100
Authors:  Zhang,Wen;  Zhang,Shao Lin;  Hu,Xiaohui;  Tam,Kin Yip
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Cancer  Phenyl butyrate  Pyruvate dehydrogenase  Pyruvate dehydrogenase kinase 1  Tumor metabolism  
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, 2016-8-23-26
Authors:  Zhang, Wen;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
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Phenyl Butyrate  Cancer  Pyruvate Dehydrogenase  Pyruvate Dehydrogenase Kinase 1  Tumor Metabolism  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
Molecular Pharmaceutics, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Tongkai Chen;  Ye Li;  Chuwen Li;  Xiang Yi;  Ruibing Wang;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite |  | TC[WOS]:13 TC[Scopus]:16 | Submit date:2018/11/06
Baicalein  Fluorescence Resonance Energy Transfer (Fret)  Micelles  Mitochondria  Multidrug Resistance-associated Protein 2 (Mrp2)  Neuroprotective Effect  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Chen, Tongkai;  Li, Ye;  Li, Chuwen;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite |  | TC[WOS]:13 TC[Scopus]:16 | Submit date:2018/10/30
micelles  baicalein  fluorescence resonance energy transfer (FRET)  multidrug resistance-associated protein 2 (MRP2)  mitochondria  neuroprotective effect