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Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice Journal article
Environmental Pollution, 2020,Volume: 265
Authors:  Liu,Jianhui;  Li,Xiangyang;  Zhou,Guiqing;  Sang,Yujian;  Zhang,Yue;  Zhao,Yanzhi;  Ge,Wei;  Sun,Zhiwei;  Zhou,Xianqing
Favorite |  | TC[WOS]:2 TC[Scopus]:5 | Submit date:2021/03/02
Histone-to-protamine exchange  L3MBTL2  P53 apoptosis pathway  RNF8-ubH2A/ubH2B pathway  Silica nanoparticles  
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:11 TC[Scopus]:9 | Submit date:2021/03/01
adipocytes  adipose tissue inflammation  autophagy  cycloartane triterpenoid  IL-1β, macrophages  NLRP3 inflammasome  
The Long and the Short of PTEN in the Regulation of Mitophagy Journal article
Frontiers in Cell and Developmental Biology, 2020,Volume: 8
Authors:  Wang,Liming;  Lu,Guang;  Shen,Han Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/02
BNIP3  mitophagy  Parkin  PINK1  PTEN  PTEN-L  
13-Methylberberine improves endothelial dysfunction by inhibiting NLRP3 inflammasome activation via autophagy induction in human umbilical vein endothelial cells Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Peng,Zhihua;  Zhan,Hong;  Shao,Yijia;  Xiong,Yan;  Zeng,Lijin;  Zhang,Cong;  Liu,Zhihao;  Huang,Zhenhua;  Su,Huanxing;  Yang,Zhen
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/01
13-Methylberberine  Anti-inflammatory  Atherosclerosis  Autophagy inducer  NLRP3 inflammasome  
Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein Journal article
Autophagy, 2020
Authors:  Hwang,Hui Yun;  Shim,Joong Sup;  Kim,Dasol;  Kwon,Ho Jeong
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/04
AMPK  antidepressant  darts  MAPT  MTOR  Sert  tauopathy  VDAC1  
SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity Journal article
Cell Death and Differentiation, 2020,Volume: 27,Issue: 1,Page: 329-344
Authors:  Zhang,Tian;  Liu,Jingxin;  Shen,Shengnan;  Tong,Qiang;  Ma,Xiaojun;  Lin,Ligen
Favorite |  | TC[WOS]:26 TC[Scopus]:23 | Submit date:2021/03/01
Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway Journal article
Stem Cell Research and Therapy, 2019,Volume: 10,Issue: 1
Authors:  Fang,Jiankang;  Zhao,Xia;  Li,Shuai;  Xing,Xingan;  Wang,Haitao;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2021/03/04
Apoptosis  Artemisinin  Bone marrow mesenchymal stem cells  CREB  Erk1/2  p90rsk  Phosphorylation  Protection  Raf  ROS  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions Journal article
Autophagy, 2019,Volume: 15,Issue: 8,Page: 1356-1375
Authors:  Kim,Tae Sung;  Jin,Yeung Bae;  Kim,Yi Sak;  Kim,Sup;  Kim,Jin Kyung;  Lee,Hye Mi;  Suh,Hyun Woo;  Choe,Jin Ho;  Kim,Young Jae;  Koo,Bon Sang;  Kim,Han Na;  Jung,Mingyu;  Lee,Sang Hee;  Kim,Don Kyu;  Chung,Chaeuk;  Son,Ji Woong;  Min,Jung Joon;  Kim,Jin Man;  Deng,Chu Xia;  Kim,Hyun Seok;  Lee,Sang Rae;  Jo,Eun Kyeong
Favorite |  | TC[WOS]:25 TC[Scopus]:24 | Submit date:2020/09/16
autophagy  mitochondrial homeostasis  Mycobacterium tuberculosis  PPARA  SIRT3