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Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice Journal article
Acta Pharmacologica Sinica, 2021,Volume: 42,Issue: 2,Page: 199-208
Authors:  Wu,Man;  Lu,Guang;  Lao,Yuan zhi;  Zhang,Hong;  Zheng,Dan;  Zheng,Zhao qing;  Yi,Juan;  Xiang,Qian;  Wang,Li ming;  Tan,Hong sheng;  Zhou,Hua;  Shen,Han ming;  Xu,Hong xi
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garciesculenxanthone B  ischemia-reperfusion injury  mitophagy  Parkin  PINK1  
Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity Journal article
Redox Biology, 2021,Volume: 38
Authors:  Xu,Jian;  Wang,Liming;  Zhang,Lihuan;  Zheng,Fang;  Wang,Fang;  Leng,Jianhang;  Wang,Keyi;  Héroux,Paul;  Shen,Han Ming;  Wu,Yihua;  Xia,Dajing
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Cell death  Cytotoxicity  MEHP  Mitochondrial ROS  PINK1-Parkin-mediated mitophagy  
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
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Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
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Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Efficient Polysulfide-Based Nanotheranostics for Triple-Negative Breast Cancer: Ratiometric Photoacoustics Monitored Tumor Microenvironment-Initiated H2S Therapy Journal article
Small, 2020,Volume: 16,Issue: 39
Authors:  Li,Jie;  Li,Xiang;  Yuan,Yan;  Wang,Qi;  Xie,Lisi;  Dai,Yunlu;  Wang,Wenjun;  Li,Lin;  Lu,Xiaomei;  Fan,Quli;  Huang,Wei
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/04
hydrogen sulfide  polysulfide  ratiometric photoacoustics  theranostics  triple-negative breast cancer  
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2021/03/01
adipocytes  adipose tissue inflammation  autophagy  cycloartane triterpenoid  IL-1β, macrophages  NLRP3 inflammasome  
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice Journal article
Environmental Pollution, 2020,Volume: 265
Authors:  Liu,Jianhui;  Li,Xiangyang;  Zhou,Guiqing;  Sang,Yujian;  Zhang,Yue;  Zhao,Yanzhi;  Ge,Wei;  Sun,Zhiwei;  Zhou,Xianqing
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Histone-to-protamine exchange  L3MBTL2  P53 apoptosis pathway  RNF8-ubH2A/ubH2B pathway  Silica nanoparticles  
Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds Journal article
Pharmacology and Therapeutics, 2020,Volume: 214
Authors:  Yu,Jie;  Zhong,Bingling;  Xiao,Qingwen;  Du,Lida;  Hou,Ying;  Sun,Hong Shuo;  Lu,Jin Jian;  Chen,Xiuping
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Cancer  Natural compounds  Programmed necrosis  
Supramolecular induction of mitochondrial aggregation and fusion Journal article
Journal of the American Chemical Society, 2020,Volume: 142,Issue: 39,Page: 16523-16527
Authors:  Sun,Chen;  Wang,Ziyi;  Yue,Ludan;  Huang,Qiaoxian;  Cheng,Qian;  Wang,Ruibing
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The combination of Panax ginseng and Angelica sinensis alleviates ischemia brain injury by suppressing NLRP3 inflammasome activation and microglial pyroptosis Journal article
Phytomedicine, 2020,Volume: 76
Authors:  Hu,Jia;  Zeng,Cheng;  Wei,Jie;  Duan,Fengqi;  Liu,Sijun;  Zhao,Yonghua;  Tan,Hongmei
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Cpa  Ischemic Stroke  Nlrp3 Inflammasomes  Pyroptosis