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Garcinone E blocks autophagy through lysosomal functional destruction in ovarian cancer cells Journal article
World Journal of Traditional Chinese Medicine, 2021,Volume: 7,Issue: 2,Page: 209-216
Authors:  Xu, Xiao Huang;  Chen, Yu Chi;  Xu, Yu Lian;  Feng, Zhe Ling;  Liu, Qian Yu;  Guo, Xia;  Lin, Li Gen;  Lu, Jin Jian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
Anticancer  autophagy  garcinone E  lysosome  TFEB  
A dual-functional nanovehicle with fluorescent tracking and its targeted killing effects on hepatocellular carcinoma cells Journal article
RSC Advances, 2021,Volume: 11,Issue: 18,Page: 10986-10995
Authors:  Zhang, Xiaojie;  Gao, Qiming;  Zhuang, Qianfen;  Zhang, Lu;  Wang, Sihan;  Du, Libo;  Yuan, Wenxi;  Wang, Caifang;  Tian, Qiu;  Yu, Hua;  Zhao, Yuming;  Liu, Yang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice Journal article
Acta Pharmacologica Sinica, 2021,Volume: 42,Issue: 2,Page: 199-208
Authors:  Wu,Man;  Lu,Guang;  Lao,Yuan zhi;  Zhang,Hong;  Zheng,Dan;  Zheng,Zhao qing;  Yi,Juan;  Xiang,Qian;  Wang,Li ming;  Tan,Hong sheng;  Zhou,Hua;  Shen,Han ming;  Xu,Hong xi
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/02
garciesculenxanthone B  ischemia-reperfusion injury  mitophagy  Parkin  PINK1  
Full-coverage regulations of autophagy by ROS: from induction to maturation Journal article
Autophagy, 2021
Authors:  Zhou, Jing;  Li, Xin Yu;  Liu, Yu Jia;  Feng, Ji;  Wu, Yong;  Shen, Han Ming;  Lu, Guo Dong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/11/30
ATGs  autophagy  oxidative regulation  protein thiols  ROS  
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng;  Zhang,Dali;  Huang,Junlan;  Luo,Fengtao;  Li,Fangfang;  Ni,Zhenhong;  Zhou,Siru;  Chen,Hangang;  Chen,Shuai;  Chen,Liang;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Liu,Peng;  Yin,Liangjun;  Qiu,Juhui;  Chen,Di;  Deng,Chuxia;  Xie,Yangli;  Luo,Lingfei;  Chen,Lin
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2020/09/16
Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Cancer Letters, 2020,Volume: 490,Page: 1-11
Authors:  Huang,Bin;  Yip,Wai Kien;  Wei,Na;  Luo,Kathy Qian
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/02
Acetyltanshinone IIA  Drug resistance  HER2 degradation  HER2-positive breast cancer  
Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity Journal article
Bioorganic and Medicinal Chemistry Letters, 2020,Volume: 30,Issue: 19
Authors:  Hong,Xiao Qiao;  He,Xiang Yu;  Tam,Kin Yip;  Chen,Wen Hua
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/04
Cathepsin B enzyme  Fluorescent anion transporter  Lysosomal alkalization  Lysosome targeting  
Cellular fate of deformable needle-shaped PLGA-PEG fibers Journal article
Acta Biomaterialia, 2020,Volume: 112,Page: 182-189
Authors:  Zhang,Bokai;  Zhu,Mingliu;  Li,Zhi;  Lung,Ping Sai;  Chrzanowski,Wojciech;  Kwok,Chi Tat;  Lu,Jian;  Li,Quan
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/09
Actin revolution  Apparent Young's modulus  Deformability  
Autophagy and parkinson’s disease Book chapter
出自: Advances in Experimental Medicine and Biology:Singapore: Springer Singapore, 2020, 页码: 21-51
Authors:  Lu,Jiahong;  Wu,Mingyue;  Yue,Zhenyu
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2021/03/02
Autophagy  Parkinson Disease  Α-synuclein  
Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation Journal article
Carcinogenesis, 2020,Volume: 41,Issue: 6,Page: 804-816
Authors:  Kai, Wang;  Yanbei, Tu;  Jian-Bo, Wan;  Meiwan, Chen;  Chengwei, He
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/12/06