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A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Glioblastoma  Jnk1/2  Noptosis  Nqo1  Tanshindiol b  
Full-coverage regulations of autophagy by ROS: from induction to maturation Journal article
Autophagy, 2021
Authors:  Zhou, Jing;  Li, Xin Yu;  Liu, Yu Jia;  Feng, Ji;  Wu, Yong;  Shen, Han Ming;  Lu, Guo Dong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/11/30
ATGs  autophagy  oxidative regulation  protein thiols  ROS  
2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2020,Volume: 152,Page: 336-347
Authors:  Yu, Jie;  Zhong, Bingling;  Jin, Long;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Li, Luoxiang;  Liu, Shuqin;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/09/17
Glioblastoma  Mam  Nqo1  Programmed Necrosis  
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
Favorite |  | TC[WOS]:6 TC[Scopus]:8 | Submit date:2021/03/01
Antiangiogenesis  Apoptosis  Dietary Compound  Glycyrrhetinic Acid  Ovarian Cancer  
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 355,Page: 1-8
Authors:  Xiaxia Wu;  Hongwei Gao;  Ying Hou;  Jie Yu;  Wen Sun;  Ying Wang;  Xiaoyan Chen;  Yulin Feng;  Qiong-ming Xu;  Xiuping Chen
Favorite |  | TC[WOS]:22 TC[Scopus]:21 | Submit date:2018/12/28
Dihydronortanshinone  Inflammation  Lps  Macrophage  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite |  | TC[WOS]:10 TC[Scopus]:12 | Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Wu, Chuanhong;  Zhao, Wenwen;  Yu, Jie;  Li, Shaojing;  Lin, Ligen;  Chen, Xiuping
Favorite |  | TC[WOS]:61 TC[Scopus]:65 | Submit date:2018/10/30
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu,Yanan;  Yuan,Renyikun;  Gao,Hongwei;  Lu,Jin Jian;  Kong,Qi;  Chen,Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/03/01
ATM/Chk2  DNA damage  iNOS/NO  L-arginine  MAM  MAPKs  
Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2017,Volume: 174,Issue: 17,Page: 2880-2896
Authors:  Gao, Hongwei;  Cui, Yankun;  Kang, Naixin;  Liu, Xin;  Liu, Yanli;  Zou, Yue;  Zhang, Ziyu;  Li, Xiaoran;  Yang, Shilin;  Li, Ji;  Wang, Chunming;  Xu, Qiong-ming;  Chen, Xiuping
Favorite |  | TC[WOS]:26 TC[Scopus]:30 | Submit date:2018/10/30