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The emerging role of KDM5A in human cancer Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Yang,Guan Jun;  Zhu,Ming Hui;  Lu,Xin Jiang;  Liu,Yan Jun;  Lu,Jian Fei;  Leung,Chung Hang;  Ma,Dik Lung;  Chen,Jiong
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Cancer  Drug resistance  Histone methylation  Jumonji C domain  KDM5A  Targeted therapy  
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
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Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Oncogene, 2021,Volume: 40,Issue: 5,Page: 937-950
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen;  Shim,Joong Sup
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Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
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drug discovery  malignant melanoma  pan-RAF  S100B-p53 interaction  synergistic  
Adsorbed hollow fiber immobilized tyrosinase for the screening of enzyme inhibitors from Pueraria lobata extract Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2021,Volume: 193
Authors:  Zhao,Cong Peng;  Yin,Shi Jun;  Chen,Guo Ying;  Wang,Yuan;  Chen,Hua;  Zhao,Jing;  Yang,Feng Qing
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Adsorbed hollow fibers  Enzyme immobilization  Inhibitor screening  Pueraria lobata  Tyrosinase  
Aqueous Extract of Salvia miltiorrhiza Bunge-Radix Puerariae Herb Pair Attenuates Osteoporosis in Ovariectomized Rats Through Suppressing Osteoclast Differentiation Journal article
Frontiers in Pharmacology, 2021,Volume: 11
Authors:  Qin,Huan;  Zhao,Wenwen;  Jiao,Yang;  Zheng,Haoyi;  Zhang,Hao;  Jin,Jingyu;  Li,Qiu;  Chen,Xiuping;  Gao,Xia;  Han,Yantao
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autophagy  osteoclast differentiation  osteoporosis  oxidative stress  Salvia miltiorrhiza bunge-radix puerariae  
Modeling Uremic Vasculopathy With Induced Pluripotent Stem Cell-Derived Endothelial Cells as a Drug Screening System Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 8
Authors:  Jang,Hye Ryoun;  Cho,Hyung Joon;  Zhou,Yang;  Shao,Ning Yi;  Lee,Kyungho;  Le,Hoai Huong Thi;  Jeon,Junseok;  Lee,Jung Eun;  Huh,Wooseong;  Ong,Sang Ging;  Lee,Won Hee;  Kim,Yoon Goo
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Chronic Kidney Disease  Endothelial Cells  Induced Pluripotent Stem Cells  Uremic Toxin  Uremic Vasculopathy  
Recent applications of magnetic solid phase extraction in sample preparation for phytochemical analysis Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2021,Volume: 192
Authors:  Yin,Shi Jun;  Zhao,Jing;  Yang,Feng Qing
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Magnetic solid-phase extraction  Modified magnetic nanoparticle  Phytochemical analysis  Sample pretreatment  
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Drug Discovery Today, 2021
Authors:  Wu,Puhua;  Zhou,Yan;  Guo,Yizhen;  Zhang,Shao Lin;  Tam,Kin Yip
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