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Macrocephatriolides A and B: Two Guaianolide Trimers from Ainsliaea macrocephala as PTP1B Inhibitors and Insulin Sensitizers Journal article
Journal of Organic Chemistry, 2021,Volume: 86,Issue: 24,Page: 17782-17789
Authors:  Ren, Yong Mei;  Zhang, Rui;  Feng, Zheling;  Ke, Chang Qiang;  Yao, Sheng;  Tang, Chunping;  Lin, Ligen;  Ye, Yang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
Favorite |  | TC[WOS]:1 TC[Scopus]:3 | Submit date:2021/03/02
Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Immobilized Kallikrein Microreactor Based on Capillary Electrophoresis for Online Enzyme Kinetics Analysis and Inhibitor Screening Journal article
Chromatographia, 2021,Volume: 84,Issue: 12,Page: 1141-1150
Authors:  Chen, Guo Ying;  Zhang, Hao;  Zhang, Chun Yan;  Wang, Yuan;  Zhao, Cong Peng;  Chen, Hua;  Yang, Feng Qing;  Hu, Yuan Jia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Capillary Electrophoresis  Enzyme Assay  Immobilized Enzyme Microreactor  Kallikrein  Molecular Docking  
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Liu, Jingxin;  Zhang, Tian;  Zhu, Jianzhong;  Ruan, Shuangchen;  Li, Rongsong;  Guo, Bing;  Lin, Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Hepatocytes  Honokiol  Lipid Accumulation  Lipolysis  Lipophagy  Sirt3  
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:  Meng, Ya;  Song, Chengcheng;  Ren, Zhili;  Li, Xiaohong;  Yang, Xiangyu;  Ai, Nana;  Yang, Yang;  Wang, Dongjin;  Zhan, Meixiao;  Wang, Jiaxian;  Lei, Chon Lok;  Liu, Weiwei;  Ge, Wei;  Lu, Ligong;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
International Immunopharmacology, 2021,Volume: 101
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping;  Chen, Fengyang;  Alam, Md Masud;  Faustman, Denise L.;  Oppenheim, Joost J.;  Chen, Xin
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2  
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Wang, Guohao;  Xie, Lisi;  Li, Bei;  Sang, Wei;  Yan, Jie;  Li, Jie;  Tian, Hao;  Li, Wenxi;  Zhang, Zhan;  Tian, Ye;  Dai, Yunlu
Favorite |  | TC[WOS]:1 TC[Scopus]:3 | Submit date:2021/12/08
Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:  Zhao, Yuxin;  Wang, Haiyong;  He, Chengwei
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Drug Resistance  Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor  Non-small Cell Lung Cancer  Targeted Therapy  
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells Journal article
Stem Cell Research and Therapy, 2021,Volume: 12,Issue: 1
Authors:  Zhang, Yumeng;  Xu, Jiaqi;  Ren, Zhili;  Meng, Ya;  Liu, Weiwei;  Lu, Ligong;  Zhou, Zhou;  Chen, Guokai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/12/09
Casein Kinase 1 (Ck1)  Human Embryonic Stem Cells  Kinase Inhibitor  Nicotinamide  Pancreatic Progenitors  Rho-associated Protein Kinase (Rock)  
Decabromodiphenyl ether induces male reproductive toxicity by activating mitochondrial apoptotic pathway through glycolipid metabolism dysbiosis Journal article
Chemosphere, 2021,Volume: 285
Authors:  Zhang, Yue;  Li, Xiangyang;  Jing, Li;  Zhou, Guiqing;  Sang, Yujian;  Gao, Leqiang;  Jiang, Shuqin;  Shi, Zhixiong;  Ge, Wei;  Sun, Zhiwei;  Zhou, Xianqing
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Apoptosis  Bde-209  Glycolipid Metabolism  Male Reproductive Toxicity  Scap/srebp-1 Pathways