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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3 beta and the ERK Pathway Journal article
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2017,Volume: 37,Issue: 4,Page: 655-664
Authors:  Yu, Jie;  Zheng, Jiacheng;  Lin, Jiajia;  Jin, Linlu;  Yu, Rui;  Mak, Shinghung;  Hu, Shengquan;  Sun, Hongya;  Wu, Xiang;  Zhang, Zaijun;  Lee, Mingyuen;  Tsim, Wahkeung;  Su, Wei;  Zhou, Wenhua;  Cui, Wei;  Han, Yifan;  Wang, Qinwen
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2018/10/30
Indirubin-3-oxime  H2O2  GSK3 beta  PI3-K  ERK  
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway Journal article
Cellular and Molecular Neurobiology, 2017,Volume: 37,Issue: 4,Page: 655-664
Authors:  Yu J.;  Zheng J.;  Lin J.;  Jin L.;  Yu R.;  Mak S.;  Hu S.;  Sun H.;  Wu X.;  Zhang Z.;  Lee M.;  Tsim W.;  Su W.;  Zhou W.;  Cui W.;  Han Y.;  Wang Q.
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2018/11/06
ERK  GSK3β  H2O2  Indirubin-3-oxime  PI3-K  
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β Journal article
Journal of Molecular Neuroscience, 2015,Volume: 57,Issue: 4,Page: 561–570
Authors:  Hu S.;  Cui W.;  Zhang Z.;  Mak S.;  Xu D.;  Li G.;  Hu Y.;  Wang Y.;  Lee M.;  Tsim K.W.;  Han Y.
Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/10/30
6ohda  Gsk3β  Indirubin-3-oxime  Mef2d  Neuroprotection  Parkinson’s Disease  
Research progress on effects of indirubin and its structurally similar compounds on anticancer and neuroprotection Journal article
Chinese Traditional and Herbal Drugs, 2014,Volume: 45,Issue: 16,Page: 2404-2411
Authors:  Wang,Ying;  Sa,Fei;  Chan,Yuet Wa;  Lee,Ming Yuen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Anticancer  Cyclin-dependent kinases  Glycogen synthase kinase-3  Indirubin  Neurodegeneration disease  
New perspective on the dual functions of indirubins in cancer therapy and neuroprotection Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 9,Page: 1213-1219
Authors:  Wang Y.;  Hoi P.M.;  Chan J.Y.-W.;  Lee S.M.-Y.
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2018/11/06
Cancer  Cdks  Dual Function  Gsk-3  Indirubin  Neurodegeneration  
Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model Journal article
Journal of Ethnopharmacology, 2010,Volume: 131,Issue: 2,Page: 242
Authors:  Alex D.;  Lam I.K.;  Lin Z.;  Lee S.M.Y.
Favorite |  | TC[WOS]:33 TC[Scopus]:38 | Submit date:2018/10/30
Anti-angiogenesis  Apoptosis  Indirubin  Zebrafish  
USES OF INDOLE-KETONES OR INDOLIDONES AS NEURO-PROTECTIVE DRUGS Patent
专利类型: 发明专利, 专利号: US20140271480A1, 申请日期: 2012-10-25, 公开日期: 2014-09-18
Authors:  Ming Yuen Lee;  Yifan Han;  Chung Lit Choi;  Zaijun Zhang;  Wei Cui
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/07
Uses of indole-ketones or indolidones as neuro-protective drugs Patent
专利类型: 发明专利, 专利号: US9486440B2, 申请日期: 2012-10-25, 公开日期: 2016-11-08
Authors:  Ming Yuen Lee;  Yifan Han;  Chung Lit Choi;  Zaijun Zhang;  Wei Cui
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/07