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Aqueous Extract of Salvia miltiorrhiza Bunge-Radix Puerariae Herb Pair Attenuates Osteoporosis in Ovariectomized Rats Through Suppressing Osteoclast Differentiation Journal article
Frontiers in Pharmacology, 2021,Volume: 11
Authors:  Qin,Huan;  Zhao,Wenwen;  Jiao,Yang;  Zheng,Haoyi;  Zhang,Hao;  Jin,Jingyu;  Li,Qiu;  Chen,Xiuping;  Gao,Xia;  Han,Yantao
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autophagy  osteoclast differentiation  osteoporosis  oxidative stress  Salvia miltiorrhiza bunge-radix puerariae  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
European Journal of Pharmaceutics and Biopharmaceutics, 2021,Volume: 158,Page: 336-346
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
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Dissolution profile  Machine learning  molecular dynamics (MD) simulations  Pharmacokinetic modeling  Solid dispersion  
Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy Journal article
International Journal of Pharmaceutics, 2020,Volume: 589
Authors:  Luo,Kaipei;  Yin,Shaoping;  Zhang,Ruixia;  Yu,Hua;  Wang,Guangji;  Li,Juan
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Enhanced anticancer efficacy  Enzyme-sensitive  Hyaluronic acid  Polymeric conjugates  Tumor targeting  
ROS-initiated chemiluminescence-driven payload release from macrocycle-based Azo-containing polymer nanocapsules Journal article
Journal of Materials Chemistry B, 2020,Volume: 8,Issue: 38,Page: 8878-8883
Authors:  Sun,Chen;  Wang,Ziyi;  Yue,Ludan;  Huang,Qiaoxian;  Lu,Siyu;  Wang,Ruibing
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Macrocycle-Based Polymer Nanocapsules for Hypoxia-Responsive Payload Delivery Journal article
ACS Materials Letters, 2020,Volume: 2,Issue: 3,Page: 266-271
Authors:  Sun,Chen;  Yue,Ludan;  Cheng,Qian;  Wang,Ziyi;  Wang,Ruibing
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Size effect of curcumin nanocrystals on dissolution, airway mucosa penetration, lung tissue distribution and absorption by pulmonary delivery Journal article
Colloids and Surfaces B: Biointerfaces, 2020,Volume: 186
Authors:  He,Yuan;  Liang,Yingmin;  Mak,Judith Choi Wo;  Liao,Yonghong;  Li,Ting;  Yan,Ru;  Li,Hai Feng;  Zheng,Ying
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Förster resonance energy transfer (FRET)  Lung absorption  Nanocrystals  Pulmonary delivery  Size effect  
Electrochemical Quantitation of Supramolecular Excipient@Drug Complexation: A General Assay Strategy Based on Competitive Host Binding with Surface-Immobilized Redox Guest Journal article
Analytical Chemistry, 2020,Volume: 92,Issue: 2,Page: 2168-2175
Authors:  Qi,Lin;  Wang,Ruibing;  Yu,Hua Zhong
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Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
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3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
Polymeric nanoparticles-based brain delivery with improved therapeutic efficacy of ginkgolide b in parkinson’s disease Journal article
International Journal of Nanomedicine, 2020,Volume: 15,Page: 10453-10467
Authors:  Zhao,Yuying;  Xiong,Sha;  Liu,Piaoxue;  Liu,Wei;  Wang,Qun;  Liu,Yao;  Tan,Hanxu;  Chen,Xiaojia;  Shi,Xuguang;  Wang,Qi;  Chen,Tongkai
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Blood–brain barrier  Drug delivery system  Endocytosis  PD treatment  Zebrafish  
Switching On and Off Macrophages by a “Bridge-Burning” Coating Improves Bone-Implant Integration under Osteoporosis Journal article
Advanced Functional Materials, 2020
Authors:  Wang,Zhenzhen;  Niu,Yiming;  Tian,Xuejiao;  Yu,Na;  Yin,Xiaoyu;  Xing,Zhen;  Li,Yurong;  Dong,Lei;  Wang,Chunming
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bioresponsive materials  glucomannan polysaccharides  macrophages  osseointegration