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Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:  Meng, Ya;  Song, Chengcheng;  Ren, Zhili;  Li, Xiaohong;  Yang, Xiangyu;  Ai, Nana;  Yang, Yang;  Wang, Dongjin;  Zhan, Meixiao;  Wang, Jiaxian;  Lei, Chon Lok;  Liu, Weiwei;  Ge, Wei;  Lu, Ligong;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells Journal article
Stem Cell Research and Therapy, 2021,Volume: 12,Issue: 1
Authors:  Zhang, Yumeng;  Xu, Jiaqi;  Ren, Zhili;  Meng, Ya;  Liu, Weiwei;  Lu, Ligong;  Zhou, Zhou;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/09
Casein kinase 1 (CK1)  Human embryonic stem cells  Kinase inhibitor  Nicotinamide  Pancreatic progenitors  Rho-associated protein kinase (ROCK)  
Protocol for intracellular and extracellular metabolite detection in human embryonic stem cells Journal article
STAR Protocols, 2021,Volume: 2,Issue: 3
Authors:  Xu, Faxiang;  Song, Chengcheng;  Liu, Weiwei;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Cell culture  Cell Differentiation  Flow Cytometry/Mass Cytometry  Metabolism  Metabolomics  Stem Cells  
Human ESC-derived MSCs enhance fat engraftment by promoting adipocyte reaggregation, secreting CCL2 and mobilizing macrophages Journal article
Biomaterials, 2021,Volume: 272
Authors:  Borkar, Roma;  Wang, Xiaoyan;  Zheng, Dejin;  Miao, Zhengqiang;  Zhang, Zhenwu;  Li, Enqin;  Wu, Yaojiong;  Xu, Ren He
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
Fat engraftment  Human embryonic stem cells  Macrophage  Mesenchymal stem cells  
Knockout of Dip2c in murine ES cell line IBMSe001-B-1 by CRISPR/Cas9 genome editing technology Journal article
Stem Cell Research, 2021,Volume: 53
Authors:  Yao, Mingze;  Su, Pengfei;  Li, Zhengfeng;  Cui, Xiaogang;  Yang, Qian;  Xing, Xiaoyu;  Lei, Yu;  Lian, Mengqiao;  Ren, Tinglin;  Wang, Xiedong;  Zheng, Yaowu;  Wu, Changxin
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/02
Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Subtype-specific cardiomyocytes for precision medicine: Where are we now? Journal article
Stem Cells, 2020,Volume: 38,Issue: 7,Page: 822-833
Authors:  Zhao,Ming Tao;  Shao,Ning Yi;  Garg,Vidu
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2021/03/04
Atrial Cardiomyocytes  Human Pluripotent Stem Cells  Nodal Cardiomyocytes  Subtype-specific Cardiomyocytes  Ventricular Cardiomyocytes  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai;  Kwok,Hang Fai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Embryonic stem cell  Peptide modification  Pluripotency  Self-renewal  Venom peptide  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2020/09/16
Defined Factors  Human Embryonic Stem Cells  Keratinocyte Differentiation  
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal article
Cell Reports, 2019,Volume: 29,Issue: 11,Page: 3374-3384.e5
Authors:  Yang,Yang;  Ren,Zhili;  Xu,Faxiang;  Meng,Ya;  Zhang,Yumeng;  Ai,Nana;  Long,Yan;  Fok,Hio Ian;  Deng,Chunhao;  Zhao,Xianyang;  Huang,Liancheng;  Zhao,Qi;  Wang,Jiaxian;  Liu,Weiwei;  Ge,Wei;  Chen,Guokai
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/02
Cardiomyocyte  Casein Kinase Ii  Heterogeneity  Human Embryonic Stem Cells  Igf  Insulin  Mesoderm  Pi3k  Temporal Regulation  Wnt