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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite |  | TC[WOS]:4 TC[Scopus]:7 | Submit date:2020/09/16
Brca1  Breast Cancer  Dna Damage  Hdac  Histone Deacetylase  Reactive Oxygen Species  Synthetic Lethality  
Lasing from Mechanically Exfoliated 2D Homologous Ruddlesden–Popper Perovskite Engineered by Inorganic Layer Thickness Journal article
Advanced Materials, 2019,Volume: 31,Issue: 39
Authors:  Liang,Yin;  Shang,Qiuyu;  Wei,Qi;  Zhao,Liyun;  Liu,Zhen;  Shi,Jia;  Zhong,Yangguang;  Chen,Jie;  Gao,Yan;  Li,Meili;  Liu,Xinfeng;  Xing,Guichuan;  Zhang,Qing
Favorite |  | TC[WOS]:31 TC[Scopus]:31 | Submit date:2021/03/11
2D semiconductors  carrier dynamics  lasing  layered materials  microlasers  Ruddlesden–Popper perovskites  
Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 13,Page: 3952-3965
Authors:  Dapeng Hao;  Jingjing Li;  Jianlin Wang;  Yuan Meng;  Zhiqiang Zhao;  Chao Zhang;  Kai Miao;  Chuxia Deng;  Benjamin K. Tsang;  Li Wang;  Li-jun Di
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2020/05/21
Ovarian Cancer  Estrogen Signaling  Deficiency Of Homologous-recombination  Chemotherapy  Hormone Replacement  
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas Journal article
Cell Reports, 2018,Volume: 23,Issue: 1,Page: 239-254.e6
Authors:  Knijnenburg T.A.;  Wang L.;  Zimmermann M.T.;  Chambwe N.;  Gao G.F.;  Cherniack A.D.;  Fan H.;  Shen H.;  Way G.P.;  Greene C.S.;  Liu Y.;  Akbani R.;  Feng B.;  Donehower L.A.;  Miller C.;  Shen Y.;  Karimi M.;  Chen H.;  Kim P.;  Jia P.;  Shinbrot E.;  Zhang S.;  Liu J.;  Hu H.;  Bailey M.H.;  Yau C.;  Wolf D.;  Zhao Z.;  Weinstein J.N.;  Li L.;  Ding L.;  Mills G.B.;  Laird P.W.;  Wheeler D.A.;  Shmulevich I.;  Caesar-Johnson S.J.;  Demchok J.A.;  Felau I.;  Kasapi M.;  Ferguson M.L.;  Hutter C.M.;  Sofia H.J.;  Tarnuzzer R.;  Wang Z.;  Yang L.;  Zenklusen J.C.;  Zhang J.J.;  Chudamani S.;  Lolla L.;  Naresh R.;  Pihl T.;  Sun Q.;  Wan Y.;  Wu Y.;  Cho J.;  DeFreitas T.;  Frazer S.;  Gehlenborg N.;  Getz G.;  Heiman D.I.;  Kim J.;  Lawrence M.S.;  Lin P.;  Meier S.;  Noble M.S.;  Saksena G.;  Voet D.;  Zhang H.;  Bernard B.;  Dhankani V.;  Knijnenburg T.;  Kramer R.;  Leinonen K.;  Miller M.;  Reynolds S.;  Thorsson V.;  Zhang W.;  Broom B.M.;  Hegde A.M.;  Ju Z.;  Kanchi R.S.;  Korkut A.;  Li J.;  Liang H.;  Ling S.;  Liu W.;  Lu Y.;  Ng K.-S.;  Rao A.;  Ryan M.;  Wang J.;  Zhang J.;  Abeshouse A.;  Armenia J.;  Chakravarty D.;  Chatila W.K.;  de Bruijn I.;  Gao J.;  Gross B.E.;  Heins Z.J.;  Kundra R.;  La K.;  Ladanyi M.;  Luna A.;  Nissan M.G.;  Ochoa A.;  Phillips S.M.;  Reznik E.;  Sanchez-Vega F.;  Sander C.;  Schultz N.;  Sheridan R.;  Sumer S.O.;  Sun Y.;  Taylor B.S.;  Anur P.;  Peto M.;  Spellman P.;  Benz C.;  Stuart J.M.;  Wong C.K.;  Hayes D.N.;  Parker J.S.;  Wilkerson M.D.;  Ally A.;  Balasundaram M.;  Bowlby R.;  Brooks D.;  Carlsen R.;  Chuah E.;  Dhalla N.;  Holt R.;  Jones S.J.M.;  Kasaian K.;  Lee D.;  Ma Y.;  Marra M.A.;  Mayo M.;  Moore R.A.;  Mungall A.J.;  Mungall K.;  Robertson A.G.;  Sadeghi S.;  Schein J.E.;  Sipahimalani P.;  Tam A.;  Thiessen N.;  Tse K.;  Wong T.;  Berger A.C.;  Beroukhim R.;  Cibulskis C.;  Gabriel S.B.;  Ha G.;  Meyerson M.;  Schumacher S.E.;  Shih J.;  Kucherlapati M.H.;  Kucherlapati R.S.;  Baylin S.;  Cope L.;  Danilova L.;  Bootwalla M.S.;  Lai P.H.;  Maglinte D.T.;  Van Den Berg D.J.;  Weisenberger D.J.;  Auman J.T.;  Balu S.;  Bodenheimer T.;  Fan C.;  Hoadley K.A.;  Hoyle A.P.;  Jefferys S.R.;  Jones C.D.;  Meng S.;  Mieczkowski P.A.;  Mose L.E.;  Perou A.H.;  Perou C.M.;  Roach J.;  Shi Y.;  Simons J.V.;  Skelly T.;  Soloway M.G.;  Tan D.;  Veluvolu U.;  Hinoue T.;  Zhou W.;  Bellair M.;  Chang K.;  Covington K.;  Creighton C.J.;  Dinh H.;  Doddapaneni H.;  Drummond J.;  Gibbs R.A.;  Glenn R.;  Hale W.;  Han Y.;  Hu J.;  Korchina V.;  Lee S.;  Lewis L.;  Li W.;  Liu X.;  Morgan M.;  Morton D.;  Muzny D.;  Santibanez J.;  Sheth M.;  Wang M.;  Xi L.;  Zhao F.;  Hess J.;  Appelbaum E.L.;  Bailey M.;  Cordes M.G.;  Fronick C.C.;  Fulton L.A.;  Fulton R.S.;  Kandoth C.;  Mardis E.R.;  McLellan M.D.;  Miller C.A.;  Schmidt H.K.;  Wilson R.K.;  Crain D.;  Curley E.;  Gardner J.;  Lau K.;  Mallery D.;  Morris S.;  Paulauskis J.;  Penny R.;  Shelton C.;  Shelton T.;  Sherman M.;  Thompson E.;  Yena P.;  Bowen J.;  Gastier-Foster J.M.;  Gerken M.;  Leraas K.M.;  Lichtenberg T.M.;  Ramirez N.C.;  Wise L.;  Zmuda E.;  Corcoran N.;  Costello T.;  Hovens C.;  Carvalho A.L.;  de Carvalho A.C.;  Fregnani J.H.;  Longatto-Filho A.;  Reis R.M.;  Scapulatempo-Neto C.;  Silveira H.C.S.;  Vidal D.O.;  Burnette A.;  Eschbacher J.;  Hermes B.;  Noss A.;  Singh R.;  Anderson M.L.;  Castro P.D.;  Ittmann M.;  Huntsman D.;  Kohl B.;  Le X.;  Thorp R.;  Andry C.;  Duffy E.R.;  Lyadov V.;  Paklina O.;  Setdikova G.;  Shabunin A.;  Tavobilov M.;  McPherson C.;  Warnick R.;  Berkowitz R.;  Cramer D.;  Feltmate C.;  Horowitz N.;  Kibel A.;  Muto M.;  Raut C.P.;  Malykh A.;  Barnholtz-Sloan J.S.;  Barrett W.;  Devine K.;  Fulop J.;  Ostrom Q.T.;  Shimmel K.;  Wolinsky Y.;  Sloan A.E.;  De Rose A.;  Giuliante F.;  Goodman M.;  Karlan B.Y.;  Hagedorn C.H.;  Eckman J.;  Harr J.;  Myers J.;  Tucker K.;  Zach L.A.;  Deyarmin B.;  Kvecher L.;  Larson C.;  Mural R.J.;  Somiari S.;  Vicha A.;  Zelinka T.;  Bennett J.;  Iacocca M.;  Rabeno B.;  Swanson P.;  Latour M.;  Lacombe L.;  Tetu B.;  Bergeron A.;  McGraw M.;  Staugaitis S.M.;  Chabot J.;  Hibshoosh H.;  Sepulveda A.;  Su T.;  Wang T.;  Potapova O.;  Voronina O.;  Desjardins L.;  Mariani O.;  Roman-Roman S.;  Sastre X.;  Stern M.-H.;  Cheng F.;  Signoretti S.;  Berchuck A.;  Bigner D.;  Lipp E.;  Marks J.;  McCall S.;  McLendon R.;  Secord A.;  Sharp A.;  Behera M.;  Brat D.J.;  Chen A.;  Delman K.;  Force S.;  Khuri F.;  Magliocca K.;  Maithel S.;  Olson J.J.;  Owonikoko T.;  Pickens A.;  Ramalingam S.;  Shin D.M.;  Sica G.;  Van Meir E.G.;  Zhang H.;  Eijckenboom W.;  Gillis A.;  Korpershoek E.;  Looijenga L.;  Oosterhuis W.;  Stoop H.;  van Kessel K.E.;  Zwarthoff E.C.;  Calatozzolo C.;  Cuppini L.;  Cuzzubbo S.;  DiMeco F.;  Finocchiaro G.;  Mattei L.;  Perin A.;  Pollo B.;  Chen C.;  Houck J.;  Lohavanichbutr P.;  Hartmann A.;  Stoehr C.;  Stoehr R.;  Taubert H.;  Wach S.;  Wullich B.;  Kycler W.;  Murawa D.;  Wiznerowicz M.;  Chung K.;  Edenfield W.J.;  Martin J.;  Baudin E.;  Bubley G.;  Bueno R.;  De Rienzo A.;  Richards W.G.;  Kalkanis S.;  Mikkelsen T.;  Noushmehr H.;  Scarpace L.;  Girard N.;  Aymerich M.;  Campo E.;  Gine E.;  Guillermo A.L.;  Van Bang N.;  Hanh P.T.;  Phu B.D.;  Tang Y.;  Colman H.;  Evason K.;  Dottino P.R.;  Martignetti J.A.;  Gabra H.;  Juhl H.;  Akeredolu T.;  Stepa S.;  Hoon D.;  Ahn K.;  Kang K.J.;  Beuschlein F.;  Breggia A.;  Birrer M.;  Bell D.;  Borad M.;  Bryce A.H.;  Castle E.;  Chandan V.;  Cheville J.;  Copland J.A.;  Farnell M.;  Flotte T.;  Giama N.;  Ho T.;  Kendrick M.;  Kocher J.-P.;  Kopp K.;  Moser C.;  Nagorney D.;  O'Brien D.;  O'Neill B.P.;  Patel T.;  Petersen G.;  Que F.;  Rivera M.;  Roberts L.;  Smallridge R.;  Smyrk T.;  Stanton M.;  Thompson R.H.;  Torbenson M.;  Yang J.D.;  Zhang L.;  Brimo F.;  Ajani J.A.;  Gonzalez A.M.A.;  Behrens C.;  Bondaruk J.;  Broaddus R.;  Czerniak B.;  Esmaeli B.;  Fujimoto J.;  Gershenwald J.;  Guo C.;  Lazar A.J.;  Logothetis C.;  Meric-Bernstam F.;  Moran C.;  Ramondetta L.;  Rice D.;  Sood A.;  Tamboli P.;  Thompson T.;  Troncoso P.;  Tsao A.;  Wistuba I.;  Carter C.;  Haydu L.;  Hersey P.;  Jakrot V.;  Kakavand H.;  Kefford R.;  Lee K.;  Long G.;  Mann G.;  Quinn M.;  Saw R.;  Scolyer R.;  Shannon K.;  Spillane A.;  Stretch J.;  Synott M.;  Thompson J.;  Wilmott J.;  Al-Ahmadie H.;  Chan T.A.;  Ghossein R.;  Gopalan A.;  Levine D.A.;  Reuter V.;  Singer S.;  Singh B.;  Tien N.V.;  Broudy T.;  Mirsaidi C.;  Nair P.;  Drwiega P.;  Miller J.;  Smith J.;  Zaren H.;  Park J.-W.;  Hung N.P.;  Kebebew E.;  Linehan W.M.;  Metwalli A.R.;  Pacak K.;  Pinto P.A.;  Schiffman M.;  Schmidt L.S.;  Vocke C.D.;  Wentzensen N.;  Worrell R.;  Yang H.;  Moncrieff M.;  Goparaju C.;  Melamed J.;  Pass H.;  Botnariuc N.;  Caraman I.;  Cernat M.;  Chemencedji I.;  Clipca A.;  Doruc S.;  Gorincioi G.;  Mura S.;  Pirtac M.;  Stancul I.;  Tcaciuc D.;  Albert M.;  Alexopoulou I.;  Arnaout A.;  Bartlett J.;  Engel J.;  Gilbert S.;  Parfitt J.;  Sekhon H.;  Thomas G.;  Rassl D.M.;  Rintoul R.C.;  Bifulco C.;  Tamakawa R.;  Urba W.;  Hayward N.;  Timmers H.;  Antenucci A.;  Facciolo F.;  Grazi G.;  Marino M.;  Merola R.;  de Krijger R.;  Gimenez-Roqueplo A.-P.;  Piche A.;  Chevalier S.;  McKercher G.;  Birsoy K.;  Barnett G.;  Brewer C.;  Farver C.;  Naska T.;  Pennell N.A.;  Raymond D.;  Schilero C.;  Smolenski K.;  Williams F.;  Morrison C.;  Borgia J.A.;  Liptay M.J.;  Pool M.;  Seder C.W.;  Junker K.;  Omberg L.;  Dinkin M.;  Manikhas G.;  Alvaro D.;  Bragazzi M.C.;  Cardinale V.;  Carpino G.;  Gaudio E.;  Chesla D.;  Cottingham S.;  Dubina M.;  Moiseenko F.;  Dhanasekaran R.;  Becker K.-F.;  Janssen K.-P.;  Slotta-Huspenina J.;  Abdel-Rahman M.H.;  Aziz D.;  Bell S.;  Cebulla C.M.;  Davis A.;  Duell R.;  Elder J.B.;  Hilty J.;  Kumar B.;  Lang J.;  Lehman N.L.;  Mandt R.;  Nguyen P.;  Pilarski R.;  Rai K.;  Schoenfield L.;  Senecal K.;  Wakely P.;  Hansen P.;  Lechan R.;  Powers J.;  Tischler A.;  Grizzle W.E.;  Sexton K.C.;  Kastl A.;  Henderson J.;  Porten S.;  Waldmann J.;  Fassnacht M.;  Asa S.L.;  Schadendorf D.;  Couce M.;  Graefen M.;  Huland H.;  Sauter G.;  Schlomm T.;  Simon R.;  Tennstedt P.;  Olabode O.;  Nelson M.;  Bathe O.;  Carroll P.R.;  Chan J.M.;  Disaia P.;  Glenn P.;  Kelley R.K.;  Landen C.N.;  Phillips J.;  Prados M.;  Simko J.;  Smith-McCune K.;  VandenBerg S.;  Roggin K.;  Fehrenbach A.;  Kendler A.;  Sifri S.;  Steele R.;  Jimeno A.;  Carey F.;  Forgie I.;  Mannelli M.;  Carney M.;  Hernandez B.;  Campos B.;  Herold-Mende C.;  Jungk C.;  Unterberg A.;  von Deimling A.;  Bossler A.;  Galbraith J.;  Jacobus L.;  Knudson M.;  Knutson T.;  Ma D.;  Milhem M.;  Sigmund R.;  Godwin A.K.;  Madan R.;  Rosenthal H.G.;  Adebamowo C.;  Adebamowo S.N.;  Boussioutas A.;  Beer D.;  Giordano T.;  Mes-Masson A.-M.;  Saad F.;  Bocklage T.;  Landrum L.;  Mannel R.;  Moore K.;  Moxley K.;  Postier R.;  Walker J.;  Zuna R.;  Feldman M.;  Valdivieso F.;  Dhir R.;  Luketich J.;  Pinero E.M.M.;  Quintero-Aguilo M.;  Carlotti C.G.;  Dos Santos J.S.;  Kemp R.;  Sankarankuty A.;  Tirapelli D.;  Catto J.;  Agnew K.;  Swisher E.;  Creaney J.;  Robinson B.;  Shelley C.S.;  Godwin E.M.;  Kendall S.;  Shipman C.;  Bradford C.;  Carey T.;  Haddad A.;  Moyer J.;  Peterson L.;  Prince M.;  Rozek L.;  Wolf G.;  Bowman R.;  Fong K.M.;  Yang I.;  Korst R.;  Rathmell W.K.;  Fantacone-Campbell J.L.;  Hooke J.A.;  Kovatich A.J.;  Shriver C.D.;  DiPersio J.;  Drake B.;  Govindan R.;  Heath S.;  Ley T.;  Van Tine B.;  Westervelt P.;  Rubin M.A.;  Lee J.I.;  Aredes N.D.;  Mariamidze A.;  Monnat R.J.;  Xiao Y.;  Wang C.
Favorite |  | TC[WOS]:207 TC[Scopus]:213 | Submit date:2019/01/16
DNA damage footprints  DNA damage repair  epigenetic silencing  integrative statistical analysis  mutational signatures  protein structure analysis  somatic copy-number alterations  somatic mutations  The Cancer Genome Atlas PanCanAtlas project  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
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Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material Journal article
BIOMATERIALS, 2017,Volume: 139,Page: 39-55
Authors:  Niu, Yiming;  Li, Qiu;  Xie, Ruiyu;  Liu, Shang;  Wang, Ruibing;  Xing, Panfei;  Shi, Yuchen;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
View | Adobe PDF | Favorite |  | TC[WOS]:29 TC[Scopus]:29 | Submit date:2018/10/30
Bioactive Coating  Glucomannan Polysaccharides  Scaffold-tissue Integration  Macrophages  Osteogenesis  
CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells Journal article
Molecular Therapy - Nucleic Acids, 2016,Volume: 5
Authors:  Xianglian Ge;  Haitao Xi;  Fayu Yang;  Xiao Zhi;  Yanghua Fu;  Ding Chen;  Ren-He Xu;  Ge Lin;  Jia Qu;  Junzhao Zhao;  Feng Gu
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2018/12/20
Aav  Crispr/cas9  Homologous Recombination  Human Embryonic Stem Cells  Next Generation Sequencing  Nrl  
A mechanism for 1,4-Benzoquinone-induced genotoxicity Journal article
Oncotarget, 2016,Volume: 7,Issue: 29,Page: 46433-46447
Authors:  Son M.Y.;  Deng C.-X.;  Hoeijmarkers J.H.;  Rebel V.I.;  Hasty P.
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2018/12/13
Double Strand Break Repair  Fanconi Anemia  Replication Fork Maintenance  Type 1 Topoisomerase  
“DNA binding region“ of BRCA1 affects genetic stability through modulating the intra-S-phase checkpoint Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 2,Page: 133-143
Authors:  Masuda T.;  Xu X.;  Dimitriadis E.K.;  Lahusen T.;  Deng C.-X.
Favorite |  | TC[WOS]:0 TC[Scopus]:13 | Submit date:2018/12/13
Brca1  Dna Binding  Genomic Instability  Intra-s-phase Checkpoint  
The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition Journal article
International Journal of Oncology, 2014,Volume: 44,Issue: 3,Page: 735
Authors:  Xia Q.;  Cai Y.;  Peng R.;  Wu G.;  Shi Y.;  Jiang W.
Favorite |  | TC[WOS]:22 TC[Scopus]:25 | Submit date:2018/10/30
BRCA1  Breast cancer  Cyclin-dependent kinase 1  Poly (ADP-ribose) polymerase inhibitor