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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Foxo3a suppresses neuropeptide w expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 15,Page: 2775-2787
Authors:  Yan,Fengxia;  Wang,Rikang;  Li,Shuai;  Zhao,Xia;  Jiang,Yizhou;  Liu,Linlin;  Fang,Jiankang;  Zhen,Xuechu;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
FoxO3a  Glucocorticoids  HPA axis dysfunction  Hypothalamus  Neuropeptide W (NPW)  
Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
Favorite |  | TC[WOS]:9 TC[Scopus]:12 | Submit date:2018/12/21
Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl-2-like protein 11 and cyclin-dependent kinase inhibitor 1B Journal article
Molecular Medicine Reports, 2018,Volume: 17,Issue: 2,Page: 3109-3114
Authors:  Yan,Fengxia;  Liao,Rifang;  Lin,Shaofen;  Deng,Xianguo;  Little,Peter J.;  Zheng,Wenhua
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/04
Cell cycle phase  Forkhead box protein O3  Uveal melanoma  Uveal melanoma cells  
Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl-2-like protein 11 and cyclin-dependent kinase inhibitor 1B Journal article
MOLECULAR MEDICINE REPORTS, 2018,Volume: 17,Issue: 2,Page: 3109-3114
Authors:  Yan, Fengxia;  Liao, Rifang;  Lin, Shaofen;  Deng, Xianguo;  Little, Peter J.;  Zheng, Wenhua
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2018/10/30
uveal melanoma  forkhead box protein O3  cell cycle phase  uveal melanoma cells  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 939-956
Authors:  Zhane, Jinming;  Fang, Xiaobin;  Li, Zeyong;  Chan, Hon Fai;  Lin, Zhixiu;  Wang, Yitao;  Chen, Meiwan
View | Adobe PDF | Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2018/10/30
Poloxamer188  Tumor Micro-environment  Glutathione  Brucea Javanica  Cancer Treatment  
Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 9,Page: 6931-6943
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Farhan, Mohd;  Little, Peter;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite |  | TC[WOS]:13 TC[Scopus]:13 | Submit date:2018/10/30
Amiodarone  Foxo3a  Akt  Antiarrhythmic  Apoptosis  Neuroprotection  
The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite |  | TC[WOS]:20 TC[Scopus]:20 | Submit date:2018/10/30
Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection