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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development Journal article
Medicinal Research Reviews, 2020,Volume: 40,Issue: 6,Page: 2089-2113
Authors:  Farhan,Mohd;  Silva,Marta;  Li,Shuai;  Yan,Fengxia;  Fang,Jiankang;  Peng,Tangming;  Hu,Jim;  Tsao,Ming Sound;  Little,Peter;  Zheng,Wenhua
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
autophagy  cancer  FOXO proteins  metastasis  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas Journal article
Journal of Translational Medicine, 2019,Volume: 17,Issue: 1
Authors:  Sun X.;  Liu X.;  Xia M.;  Shao Y.;  Zhang X.D.
Adobe PDF | Favorite |  | TC[WOS]:13 TC[Scopus]:11 | Submit date:2021/03/03
Biomarker  Drug Resistance  Glioma  Macrophages  Multicellular Gene Network  Prognostic Signature  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
FOXO Signaling Pathways as Therapeutic Targets in Cancer Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 7,Page: 815-827
Authors:  Farhan, Mohd;  Wang, Haitao;  Gaur, Uma;  Little, Peter J.;  Xu, Jiangping;  Zheng, Wenhua
Favorite |  | TC[WOS]:124 TC[Scopus]:121 | Submit date:2018/10/30
Apoptosis  nuclear translocation  FOXO  cell proliferation  anticancer drugs  transcription factors  
Glutamate acting on N-methyl-D-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and Its survival signaling properties in rat hippocampal neurons Journal article
Journal of Biological Chemistry, 2009,Volume: 284,Issue: 2,Page: 855-861
Authors:  Zheng W.-H.;  Quirion R.
Favorite |  | TC[WOS]:47 TC[Scopus]:46 | Submit date:2018/12/21
Adiponectin, an Unlocking Adipocytokine Journal article
CARDIOVASCULAR THERAPEUTICS, 2009,Volume: 27,Issue: 1,Page: 59-75
Authors:  Sun, YY;  Xun, KL;  Wang, CG;  Zhao, HY;  Bi, HC;  Chen, XP;  Wang, YT
View | Adobe PDF | Favorite |  | TC[WOS]:61 TC[Scopus]:68 | Submit date:2018/11/01
Adiponecitn  Biomarker  Drug Target  Exercise  Gender Difference  Inflammation