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Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI–Mediated Anticancer Activity in NSCLC Journal article
Translational Oncology, 2019,Volume: 12,Issue: 11,Page: 1516-1524
Authors:  Yang,Zheng;  Chan,Kin Iong;  Kwok,Hang Fai;  Tam,Kin Yip
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/04
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
Favorite |  | TC[WOS]:6 TC[Scopus]:8 | Submit date:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
Tumor vasculature normalization by orally fed erlotinib to modulate the tumor microenvironment for enhanced cancer nanomedicine and immunotherapy Journal article
BIOMATERIALS, 2017,Volume: 148,Page: 69-80
Authors:  Chen, Qian;  Xu, Ligeng;  Chen, Jiawen;  Yang, Zhijuan;  Liang, Chao;  Yang, Yu;  Liu, Zhuang
Favorite |  | TC[WOS]:51 TC[Scopus]:51 | Submit date:2018/10/30
Erlotinib  Vascular normalization  Tumor microenvironment  Nanomedicine  Immunotherapy  
Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2017,Volume: 815,Page: 80-87
Authors:  Yang, Zheng;  Hu, Xiaohui;  Zhang, Shaolin;  Zhang, Wen;  Tam, Kin Yip
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/10/30
Synergism  Dichloroacetophenone  Dichloroacetate  Egfr  Apoptosis  Acquired Resistance  
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.;  Chan V.;  Zheng W.;  Little P.J.
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2018/12/21
cell signalling  GAG hyperelongation  platelet derived growth factor  proteoglycan  tinibs  transforming growth factor-β  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang,Zheng;  Tam,Kin Y.
Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2021/03/04
Dichloroacetate  Drug combination  Epidermal growth factor Receptor  Erlotinib  Gefitinib  Pyruvate dehydrogenase kinase  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang Z.;  Tam K.Y.
Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2018/12/18
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase  
Characterization of osimertinib (AZD9291)-resistant non-small cell lung cancer NCI-H1975/OSIR cell line Journal article
Oncotarget, 2016,Volume: 7,Issue: 49,Page: 81598-81610
Authors:  Tang Z.-H.;  Jiang X.-M.;  Guo X.;  Fong C.M.V.;  Chen X.;  Lu J.-J.
Favorite |  | TC[WOS]:29 TC[Scopus]:29 | Submit date:2018/12/28
Azd9291  Egfr  Navitoclax  Nsclc  Osimertinib  
Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non-small cell lung cancers Journal article
Molecular Cancer Therapeutics, 2007,Volume: 6,Issue: 10,Page: 2642-2651
Authors:  Doody J.F.;  Wang Y.;  Patel S.N.;  Joynes C.;  Sui P.L.;  Gerlak J.;  Rolser R.L.;  Li Y.;  Steiner P.;  Bassi R.;  Hicklin D.J.;  Hadari Y.R.
Favorite |  | TC[WOS]:44 TC[Scopus]:49 | Submit date:2019/01/16