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Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Cancer Letters, 2020,Volume: 490,Page: 1-11
Authors:  Huang,Bin;  Yip,Wai Kien;  Wei,Na;  Luo,Kathy Qian
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/02
Acetyltanshinone IIA  Drug resistance  HER2 degradation  HER2-positive breast cancer  
Current strategies for treating NSCLC: From biological mechanisms to clinical treatment Journal article
Cancers, 2020,Volume: 12,Issue: 6,Page: 1-24
Authors:  Li,Junnan;  Kwok,Hang Fai
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/04
Combination targeted therapy  Drug resistance mechanism  EGFR mutation  Lung cancer  
Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI–Mediated Anticancer Activity in NSCLC Journal article
Translational Oncology, 2019,Volume: 12,Issue: 11,Page: 1516-1524
Authors:  Yang,Zheng;  Chan,Kin Iong;  Kwok,Hang Fai;  Tam,Kin Yip
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/04
FAM83D promotes ovarian cancer progression and its potential application in diagnosis of invasive ovarian cancer Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019,Volume: 23,Issue: 7,Page: 4569-4581
Authors:  Qingyu Zhang;  Shan Yu;  Samson Ian Sam Lok;  Alice Sze Tsai Wong;  Yufei Jiao;  Leo Tsz On Lee
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2020/05/15
Fam83d  Nvasive Epithelial Ovarian Cancer,  Low Malignant Potential Ovarian Tumour  Molecular Diagnosis  
Angiotensin II promotes ovarian cancer spheroid formation and metastasis by upregulation of lipid desaturation and suppression of endoplasmic reticulum stress Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019,Volume: 38
Authors:  Qingyu Zhang;  Shan Yu;  Melody Man Ting Lam;  Terence Chuen Wai Poon;  Litao Sun;  Yufei Jiao;  Alice Sze Tsai Wong;  Leo Tsz On Lee
Favorite |  | TC[WOS]:30 TC[Scopus]:17 | Submit date:2020/05/15
Angiotensin Ii  Ovarian Cancer  Spheroid Formation  Lipogenesis  Endoplasmic Reticulum Stress  
Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas Journal article
Journal of Translational Medicine, 2019,Volume: 17,Issue: 1
Authors:  Sun X.;  Liu X.;  Xia M.;  Shao Y.;  Zhang X.D.
Adobe PDF | Favorite |  | TC[WOS]:14 TC[Scopus]:13 | Submit date:2021/03/03
Biomarker  Drug Resistance  Glioma  Macrophages  Multicellular Gene Network  Prognostic Signature  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:12 TC[Scopus]:11 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite |  | TC[WOS]:23 TC[Scopus]:21 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Combination strategies using EGFR-TKi in NSCLC therapy: Learning from the gap between pre-clinical results and clinical outcomes Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 2,Page: 204-216
Authors:  Yang,Zheng;  Tam,Kin Yip
Favorite |  | TC[WOS]:38 TC[Scopus]:40 | Submit date:2021/03/04
Chemotherapy  Combination  EGFR-TKi  Immunotherapy  NSCLC  Targeted therapy