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Current strategies for treating NSCLC: From biological mechanisms to clinical treatment Journal article
Cancers, 2020,Volume: 12,Issue: 6,Page: 1-24
Authors:  Li,Junnan;  Kwok,Hang Fai
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/04
Combination targeted therapy  Drug resistance mechanism  EGFR mutation  Lung cancer  
Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI–Mediated Anticancer Activity in NSCLC Journal article
Translational Oncology, 2019,Volume: 12,Issue: 11,Page: 1516-1524
Authors:  Yang,Zheng;  Chan,Kin Iong;  Kwok,Hang Fai;  Tam,Kin Yip
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/04
Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas Journal article
Journal of Translational Medicine, 2019,Volume: 17,Issue: 1
Authors:  Sun X.;  Liu X.;  Xia M.;  Shao Y.;  Zhang X.D.
Adobe PDF | Favorite |  | TC[WOS]:13 TC[Scopus]:11 | Submit date:2021/03/03
Biomarker  Drug Resistance  Glioma  Macrophages  Multicellular Gene Network  Prognostic Signature  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite |  | TC[WOS]:21 TC[Scopus]:20 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
CANCER LETTERS, 2018,Volume: 420,Page: 242-246
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
Favorite |  | TC[WOS]:50 TC[Scopus]:52 | Submit date:2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2017,Volume: 815,Page: 80-87
Authors:  Yang, Zheng;  Hu, Xiaohui;  Zhang, Shaolin;  Zhang, Wen;  Tam, Kin Yip
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/10/30
Synergism  Dichloroacetophenone  Dichloroacetate  Egfr  Apoptosis  Acquired Resistance  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite |  | TC[WOS]:25 TC[Scopus]:25 | Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite |  | TC[WOS]:29 TC[Scopus]:29 | Submit date:2018/10/30
Osimertinib  Azd9291  Autophagy  Apoptosis  Ros  
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol Journal article
International Journal of Oncology, 2016,Volume: 49,Issue: 4,Page: 1576-1588
Authors:  Xu S.-W.;  Law B.Y.K.;  Mok S.W.F.;  Leung E.L.H.;  Fan X.X.;  Coghi P.S.;  Zeng W.;  Leung C.-H.;  Ma D.-L.;  Liu L.;  Wong V.K.W.
Favorite |  | TC[WOS]:15 TC[Scopus]:18 | Submit date:2018/11/06
Autophagy  Calcium  Celastrol  Epidermal Growth Factor Receptor  Gefitinib-resistant Lung Cancer