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Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
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drug discovery  malignant melanoma  pan-RAF  S100B-p53 interaction  synergistic  
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Drug Discovery Today, 2021
Authors:  Wu,Puhua;  Zhou,Yan;  Guo,Yizhen;  Zhang,Shao Lin;  Tam,Kin Yip
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Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
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Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy Journal article
International Journal of Pharmaceutics, 2020,Volume: 589
Authors:  Luo,Kaipei;  Yin,Shaoping;  Zhang,Ruixia;  Yu,Hua;  Wang,Guangji;  Li,Juan
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Enhanced Anticancer Efficacy  Enzyme-sensitive  Hyaluronic Acid  Polymeric Conjugates  Tumor Targeting  
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong,Sha;  Li,Zhongjun;  Liu,Yao;  Wang,Qun;  Luo,Jingshan;  Chen,Xiaojia;  Xie,Zhongjian;  Zhang,Yuan;  Zhang,Han;  Chen,Tongkai
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Black Phosphorus Nanosheets  Blood-brain Barrier  Brain Targeting  Drug Delivery  Lactoferrin  
Bioorthogonal supramolecular cell-conjugation for targeted hitchhiking drug delivery Journal article
Materials Today, 2020,Volume: 40,Page: 9-17
Authors:  Gao,Cheng;  Cheng,Qian;  Wei,Jianwen;  Sun,Chen;  Lu,Siyu;  Kwong,Cheryl H.T.;  Lee,Simon M.Y.;  Zhong,Zhiyuan;  Wang,Ruibing
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Small Molecular Prodrug Amphiphile Self-Assembled AIE Dots for Cancer Theranostics Journal article
Frontiers in Bioengineering and Biotechnology, 2020,Volume: 8
Authors:  Yang,Xing;  Luo,Yuan;  Li,Sanpeng;  Xu,Xiuli;  Bao,Yingxia;  Yang,Jiaming;  Ouyang,Defang;  Fan,Xingxing;  Gong,Ping;  Cai,Lintao
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AIE  cancer  prodrug  self-assembly  theranostics  
Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy Journal article
Biomaterials, 2020,Volume: 246
Authors:  Yang,Yu;  Zhu,Wenjun;  Cheng,Liang;  Cai,Ren;  Yi,Xuan;  He,Jiaxuan;  Pan,Xiaoshu;  Yang,Lu;  Yang,Kai;  Liu,Zhuang;  Tan,Weihong;  Chen,Meiwan
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Aptamer-drug conjugates (ApDCs)  Deep tumor penetration  Photodynamic therapy (PDT)  Tumor microenvironment (TME)  
Minocycline for Depressive Symptoms: a Meta-Analysis of Randomized, Double-Blinded, Placebo-Controlled Trials Journal article
Psychiatric Quarterly, 2020,Volume: 91,Issue: 2,Page: 451-461
Authors:  Cai,Dong Bin;  Zheng,Wei;  Zhang,Qing E.;  Ng,Chee H.;  Ungvari,Gabor S.;  Huang,Xiong;  Xiang,Yu Tao
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Depressive symptoms  Meta-analysis  Minocycline  Remission  Response  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
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acetylcholinesterase  Alzheimer's disease  amyloid beta  butyrylcholinesterase  dual target inhibitor  isoquinolinium  pyridinium