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DNA damage repair system in C57BL/6 J mice is evolutionarily stable Journal article
BMC Genomics, 2021,Volume: 22,Issue: 1
Authors:  Wang, Xiaoyu;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Brca1  Brca2  C57bl/6 j  Dna Damage Repair  Evolution Selection  Variation  
Can population BRCA screening be applied in non-Ashkenazi Jewish populations? Experience in Macau population Journal article
Journal of Medical Genetics, 2021,Volume: 58,Issue: 9,Page: 587-591
Authors:  Qin, Zixin;  Kuok, Cheong Nang;  Dong, Hui;  Jiang, Luhan;  Zhang, Li;  Guo, Maoni;  Leong, Hio Kuan;  Wang, Lei;  Meng, Grace;  Wang, San Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date:2021/12/08
DNA damage  DNA repair  early diagnosis  genetic carrier screening  genetics  
An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells Journal article
Bioorganic Chemistry, 2021,Volume: 114
Authors:  Yang, Guan Jun;  Song, Ying Qi;  Wang, Wanhe;  Han, Quan Bin;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/12/08
Acetylated RelA  BRD4  NF-κB  Protein-protein interaction  TNBC  
Roles and therapeutic implications of endoplasmic reticulum stress and oxidative stress in cardiovascular diseases Journal article
Antioxidants, 2021,Volume: 10,Issue: 8
Authors:  Zhou, Yan;  Murugan, Dharmani Devi;  Khan, Haroon;  Huang, Yu;  Cheang, Wai San
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Cardiovascular diseases  Endoplasmic reticulum stress  Oxidative stress  
LncRNA DINOR is a virulence factor and global regulator of stress responses in Candida auris Journal article
Nature Microbiology, 2021,Volume: 6,Issue: 7,Page: 842-851
Authors:  Gao, Jiaxin;  Chow, Eve W.L.;  Wang, Haitao;  Xu, Xiaoli;  Cai, Chunling;  Song, Yabing;  Wang, Jianbin;  Wang, Yue
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/12/08
Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 9
Authors:  Song, Ying Qi;  Wu, Chun;  Wu, Ke Jia;  Han, Quan Bin;  Miao, Xiang Min;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
cancer  drug discovery  treatment  ubiquitination regulator  virtual screening  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/09/17
Glioblastoma  Jnk1/2  Noptosis  Nqo1  Tanshindiol b  
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes Journal article
Journal of Cellular Physiology, 2021,Volume: 236,Issue: 2,Page: 981-996
Authors:  Peng,Cheng;  Hou,Sheng Tao;  Deng,Chu Xia;  Zhang,Yandong
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/02
Demethylation  Dhx33  Gadd45a  Glycolysis  Rna Helicase  Warburg Effect  
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen;  Hu, Lingling;  Su, Sek Man;  Chan, Un In;  Miao, Kai;  Zhang, Xu;  Zhang, Aiping;  Guo, Sen;  Chen, Si;  Meng, Ya;  Deng, Min;  Hao, Wenhui;  Lei, Haipeng;  Lin, Ying;  Yang, Zhonglin;  Tang, Dongjiang;  Wong, Koon Ho;  Zhang, Xiaohua Douglas;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/11/30
Brca1/BRCA1  Mammary tumor  Mrc2  Single cell RNA-seq  Tumor heterogeneity  
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:15 TC[Scopus]:14 | Submit date:2020/09/16