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An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles Journal article
Autophagy, 2020
Authors:  Ruan,Chen;  Wang,Chenwei;  Gong,Xuanqing;  Zhang,Ying;  Deng,Wankun;  Zhou,Jiaqi;  Huang,Dengtong;  Wang,Zining;  Zhang,Qiong;  Guo,Anyuan;  Lu,Jiahong;  Gao,Jinhao;  Peng,Di;  Xue,Yu
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Autophagy  CDK4  CDK7  phosphoproteomics  protein kinase  silica nanoparticles  
Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells Journal article
ONCOLOGY LETTERS, 2018,Volume: 16,Issue: 4,Page: 4671-4678
Authors:  Yao, Jingyun;  Xiao, Jianbo;  Wei, Xing;  Lu, Yanhua
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2018/10/30
Cell Cycle Arrest  Cyclin  Cyclin-dependent Kinase  Chaetominine  K562 Cells  Sw1116 Cells  
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite |  | TC[WOS]:18 TC[Scopus]:15 | Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite |  | TC[WOS]:21 TC[Scopus]:21 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
Favorite |  | TC[WOS]:17 TC[Scopus]:15 | Submit date:2018/10/30
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
Favorite |  | TC[WOS]:17 TC[Scopus]:15 | Submit date:2018/12/21
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
View | Adobe PDF | Favorite |  | TC[WOS]:30 TC[Scopus]:40 | Submit date:2018/10/30
P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates Journal article
GENES & DEVELOPMENT, 2016,Volume: 30,Issue: 1,Page: 117-131
Authors:  Miriam Sansó;  Rebecca S. Levin;  Jesse J. Lipp;  Vivien Ya-Fan Wang;  Ann Katrin Greifenberg;  Elizabeth M. Quezada;  Akbar Ali;  Animesh Ghosh;  Stéphane Larochelle;  Tariq M. Rana;  Matthias Geyer;  Liang Tong;  Kevan M. Shokat;  Robert P. Fisher
Favorite |  | TC[WOS]:58 TC[Scopus]:61 | Submit date:2019/01/17
P-tefb  Rna Polymerase Ii  Xrn2  Chemical Genetics  Protein Phosphorylation  Transcription Termination  
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β Journal article
Journal of Molecular Neuroscience, 2015,Volume: 57,Issue: 4,Page: 561–570
Authors:  Hu S.;  Cui W.;  Zhang Z.;  Mak S.;  Xu D.;  Li G.;  Hu Y.;  Wang Y.;  Lee M.;  Tsim K.W.;  Han Y.
Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/10/30
6ohda  Gsk3β  Indirubin-3-oxime  Mef2d  Neuroprotection  Parkinson’s Disease