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An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles Journal article
Autophagy, 2021,Volume: 17,Issue: 6,Page: 1426-1447
Authors:  Ruan,Chen;  Wang,Chenwei;  Gong,Xuanqing;  Zhang,Ying;  Deng,Wankun;  Zhou,Jiaqi;  Huang,Dengtong;  Wang,Zining;  Zhang,Qiong;  Guo,Anyuan;  Lu,Jiahong;  Gao,Jinhao;  Peng,Di;  Xue,Yu
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Autophagy  Cdk4  Cdk7  Phosphoproteomics  Protein Kinase  Silica Nanoparticles  
Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells Journal article
ONCOLOGY LETTERS, 2018,Volume: 16,Issue: 4,Page: 4671-4678
Authors:  Yao, Jingyun;  Xiao, Jianbo;  Wei, Xing;  Lu, Yanhua
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2018/10/30
Cell Cycle Arrest  Cyclin  Cyclin-dependent Kinase  Chaetominine  K562 Cells  Sw1116 Cells  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite |  | TC[WOS]:23 TC[Scopus]:21 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:17 TC[Scopus]:19 | Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
Favorite |  | TC[WOS]:18 TC[Scopus]:17 | Submit date:2018/12/21
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
Favorite |  | TC[WOS]:18 TC[Scopus]:17 | Submit date:2018/10/30
Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl-2-like protein 11 and cyclin-dependent kinase inhibitor 1B Journal article
MOLECULAR MEDICINE REPORTS, 2018,Volume: 17,Issue: 2,Page: 3109-3114
Authors:  Yan, Fengxia;  Liao, Rifang;  Lin, Shaofen;  Deng, Xianguo;  Little, Peter J.;  Zheng, Wenhua
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/10/30
uveal melanoma  forkhead box protein O3  cell cycle phase  uveal melanoma cells  
Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl-2-like protein 11 and cyclin-dependent kinase inhibitor 1B Journal article
Molecular Medicine Reports, 2018,Volume: 17,Issue: 2,Page: 3109-3114
Authors:  Yan,Fengxia;  Liao,Rifang;  Lin,Shaofen;  Deng,Xianguo;  Little,Peter J.;  Zheng,Wenhua
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/04
Cell cycle phase  Forkhead box protein O3  Uveal melanoma  Uveal melanoma cells  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017,Volume: 36
Authors:  Wang, Yitao;  Qin, Xian;  Guo, Tao;  Liu, Pengpeng;  Wu, Ping;  Liu, Zhisu
Favorite |  | TC[WOS]:13 TC[Scopus]:17 | Submit date:2018/11/01
Hepatocellular carcinoma (HCC)  Cyclin dependent Kinase 16 (CDK16)  Epithelial mesenchymal transition (EMT)  E2F1 transcription factor  miR-125b-5p