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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
Favorite |  | TC[WOS]:1 TC[Scopus]:3 | Submit date:2021/03/02
Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF-κB pathways in RAW 264.7 cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhou, Chunxiu;  Zhang, Xutao;  Ruan, Cheng Chao;  Cheang, Wai San
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/09
3,3′,4,5′-tetramethoxy-trans-stilbene  3,4′,5-trimethoxy-trans-stilbene  Inflammation  Lipopolysaccharide  MAPK  NF-κB  
Anticancer effects of asiatic acid against doxorubicin-resistant breast cancer cells via an AMPK-dependent pathway in vitro Journal article
Phytomedicine, 2021,Volume: 92
Authors:  Zhu, Zhu;  Cui, Liao;  Yang, Jing;  Vong, Chi Teng;  Hu, Yuanjia;  Xiao, Jianbo;  Chan, Ging;  He, Zhiwei;  Zhong, Zhangfeng
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Asiatic Acid  Breast Cancer  Centella Asiatica  Chemoresistance  Doxorubicin  
Temperature Tolerance Electric Cell-Substrate Impedance Sensing for Joint Assessment of Cell Viability and Vitality Journal article
ACS Sensors, 2021
Authors:  Yang, Ning;  Hui, Wenhao;  Dong, Sizhe;  Zhang, Xuming;  Shao, Liyang;  Jia, Yanwei;  Mak, Pui In;  Paulo Da Silva Martins, Rui
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/10/28
Cell Viability  Cell Vitality  Drug Screening  Electric Cell-substrate Impedance Sensing (Ecis)  Temperature Tolerance  
β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Wu, Jiazhen;  Gan, Yuxuan;  Luo, Huijuan;  Xu, Nan;  Chen, Liping;  Li, Mengyao;  Guan, Fengkun;  Su, Ziren;  Lin, Zhixiu;  Xie, Jianhui;  Liu, Yuhong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
5-fluorouracil  cAMP/PKA/CREB pathway  intestinal mucositis  water transport  β-patchoulene  
Fuzhenghefuzhiyang Formula (FZHFZY) Improves Epidermal Differentiation via Suppression of the Akt/mTORC1/S6K1 Signalling Pathway in Psoriatic Models Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Lu, Yue;  Chen, Haiming;  Zhang, Junhong;  Tang, Bin;  Zhang, Hongyu;  Ma, Changju;  Tang, Xiaojuan;  Li, Li;  Wu, Jingjing;  Wei, Jianan;  Li, Shaoping;  Yang, Lei;  Han, Ling;  Lu, Chuanjian
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Akt/mTORC1/S6K1 pathway  epidermal differentiation  Fuzhenghefuzhiyang formula  imiquimod  psoriasis  
Natural alkaloid compounds as inhibitors for alpha-synuclein seeded fibril formation and toxicity Journal article
Molecules, 2021,Volume: 26,Issue: 12
Authors:  Ghanem, Simona S.;  Fayed, Hend S.;  Zhu, Qi;  Lu, Jia Hong;  Vaikath, Nishant N.;  Ponraj, Janarthanan;  Mansour, Said;  El-Agnaf, Omar M.A.
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Parkinson’s disease  Seeded fibril formation  α-synuclein  
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles Journal article
Autophagy, 2021,Volume: 17,Issue: 6,Page: 1426-1447
Authors:  Ruan,Chen;  Wang,Chenwei;  Gong,Xuanqing;  Zhang,Ying;  Deng,Wankun;  Zhou,Jiaqi;  Huang,Dengtong;  Wang,Zining;  Zhang,Qiong;  Guo,Anyuan;  Lu,Jiahong;  Gao,Jinhao;  Peng,Di;  Xue,Yu
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/02
Autophagy  Cdk4  Cdk7  Phosphoproteomics  Protein Kinase  Silica Nanoparticles  
Silica nanoparticles inducing the apoptosis via microRNA-450b-3p targeting MTCH2 in mice and spermatocyte cell Journal article
Environmental Pollution, 2021,Volume: 277
Authors:  Zhou, Guiqing;  Liu, Jianhui;  Li, Xiangyang;  Sang, Yujian;  Zhang, Yue;  Gao, Leqiang;  Wang, Ji;  Yu, Yang;  Ge, Wei;  Sun, Zhiwei;  Zhou, Xianqing
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Apoptosis Signaling Pathway  Male Reproductive Toxicity  Mirna-450b-3p  Mitochondrial Carrier Homolog 2 (Mtch2)  Silica Nanoparticles (Sinps)  
Aurora kinase A, a synthetic lethal target for precision cancer medicine Journal article
Experimental and Molecular Medicine, 2021,Volume: 53,Issue: 5,Page: 835-847
Authors:  Mou, Pui Kei;  Yang, Eun Ju;  Shi, Changxiang;  Ren, Guowen;  Tao, Shishi;  Shim, Joong Sup
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/07