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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Conditional reprogramming: next generation cell culture Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 8,Page: 1360-1381
Authors:  Wu,Xiaoxiao;  Wang,Shengpeng;  Li,Mingxing;  Li,Jing;  Shen,Jing;  Zhao,Yueshui;  Pang,Jun;  Wen,Qinglian;  Chen,Meijuan;  Wei,Bin;  Kaboli,Parham Jabbarzadeh;  Du,Fukuan;  Zhao,Qijie;  Cho,Chi Hin;  Wang,Yitao;  Xiao,Zhangang;  Wu,Xu
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
3t3-j2 Fibroblast  Conditional Reprogramming  Rock  Senescence  Y-27632  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
Authors:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
Favorite |  | TC[WOS]:19 TC[Scopus]:17 | Submit date:2019/01/15
Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Establishment and characterization of pemetrexed-resistant NCI-H460/PMT cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2019,Volume: 19,Issue: 6,Page: 731-739
Authors:  Xu,Yu Lian;  Jiang,Xiao Ming;  Zhang,Le Le;  Chen,Xiuping;  Huang,Zhang Jian;  Lu,Jin Jian
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/01
ABCB1  Chemotherapy  NSCLC  Pemetrexed  Resistance  TYMS  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor delta Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 139,Page: 384-394
Authors:  Wai San Cheang;  Wing Tak Wong;  Li Wang;  Chak Kwong Cheng;  Chi Wai Lau;  Ronald Chin Wan Ma;  Aimin Xu;  Nanping Wang;  Yu Huang;  Xiao Yu Tian
Favorite |  | TC[WOS]:19 TC[Scopus]:17 | Submit date:2020/04/09
Pparδ  Sirt1  Endothelial Dysfunction  Diet Induced Obesity  
Scalable Generation of Mesenchymal Stem Cells from Human Embryonic Stem Cells in 3D Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 10,Page: 1196-1210
Authors:  Yan, Li;  Jiang, Bin;  Li, Enqin;  Wang, Xiaoyan;  Ling, Qinjie;  Zheng, Dejin;  Park, Jung Woo;  Chen, Xin;  Cheung, Edwin;  Du, Xin;  Li, Yingcui;  Cheng, Gregory;  He, Erxing;  Xu, Ren-He
Favorite |  | TC[WOS]:16 TC[Scopus]:19 | Submit date:2018/10/30
Mesenchymal Stem Cells  Human Pluripotent Stem Cells  3d  Spheroids  Colitis  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View | Adobe PDF | Favorite |  | TC[WOS]:38 TC[Scopus]:37 | Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways Journal article
Pharmacological Reports, 2013,Volume: 65,Issue: 3,Page: 700
Authors:  Ying-Bo Li;  Jian-Li Gao;  Zhang-Feng Zhong;  Pui-Man Hoi;  Simon Ming-Yuen Lee;  Yi-Tao Wang
Favorite |  | TC[WOS]:31 TC[Scopus]:37 | Submit date:2018/10/30
Bisdemethoxycurcumin (Bdmc)  Breast Cancer  Reactive Oxidative Species (Ros)  Rhizoma Curcumae Longae