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Pharmacological inhibition of KDM5A for cancer treatment Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 226
Authors:  Yang, Guan Jun;  Wu, Jia;  Miao, Liang;  Zhu, Ming Hui;  Zhou, Qian Jin;  Lu, Xin Jiang;  Lu, Jian Fei;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
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Cancer Therapy  Drug Resistance  Histone Methylation  Lysine-specific Demethylase 5a  Screening Methods  
Metal-Phenolic Network-Enabled Lactic Acid Consumption Reverses Immunosuppressive Tumor Microenvironment for Sonodynamic Therapy Journal article
ACS Nano, 2021,Volume: 15,Issue: 10,Page: 16934-16945
Authors:  Zhang, Zhan;  Li, Bei;  Xie, Lisi;  Sang, Wei;  Tian, Hao;  Li, Jie;  Wang, Guohao;  Dai, Yunlu
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Antitumor Therapy  Lactic Acid  Metal-phenolic Network  Sonodynamic Therapy  Tumor Microenvironment  
Development of arteannuin B sustained-release microspheres for anti-tumor therapy by integrated experimental and molecular modeling approaches Journal article
Pharmaceutics, 2021,Volume: 13,Issue: 8
Authors:  Wang, Yanqing;  Huang, Weijuan;  Wang, Nannan;  Ouyang, Defang;  Xiao, Lifeng;  Zhang, Sirui;  Ou, Xiaozheng;  He, Tingsha;  Yu, Rongmin;  Song, Liyan
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Antitumor activity  Arteannuin B  Microsphere  Molecular modeling  Pharmacokinetics  PLGA  Sustained release  
TPGS and chondroitin sulfate dual-modified lipid-albumin nanosystem for targeted delivery of chemotherapeutic agent against multidrug-resistant cancer Journal article
International Journal of Biological Macromolecules, 2021,Volume: 183,Page: 1270-1282
Authors:  Luo, Kaipei;  Xu, Feng;  Yao, Tianyi;  Zhu, Jianping;  Yu, Hua;  Wang, Guangji;  Li, Juan
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Lipid-albumin nanosystem  Multidrug resistance  Targeted therapy  
Cryptotanshinone Inhibits the Growth of HCT116 Colorectal Cancer Cells Through Endoplasmic Reticulum Stress-Mediated Autophagy Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Fu, Xiaojing;  Zhao, Wenwen;  Li, Kangkang;  Zhou, Jingyi;  Chen, Xuehong
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apoptosis  autophagy  colorectal cancer  cryptotanshinone  endoplasmic reticulum stress  
Supramolecular nanovesicles for synergistic glucose starvation and hypoxia-activated gene therapy of cancer Journal article
Nanoscale, 2021,Volume: 13,Issue: 21,Page: 9570-9576
Authors:  Yue, Ludan;  Sun, Tianlei;  Yang, Kuikun;  Cheng, Qian;  Li, Junyan;  Pan, Yue;  Wang, Shu;  Wang, Ruibing
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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
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Cancer Metabolism  Proliferation  Pyruvate Dehydrogenase Kinase  Structure-activity Relationship  
Quercetin induces p53-independent cancer cell death through lysosome activation by the transcription factor EB and Reactive Oxygen Species-dependent ferroptosis Journal article
British Journal of Pharmacology, 2021,Volume: 178,Issue: 5,Page: 1133-1148
Authors:  Wang,Zi Xuan;  Ma,Jing;  Li,Xin Yu;  Wu,Yong;  Shi,Huan;  Chen,Yao;  Lu,Guang;  Shen,Han Ming;  Lu,Guo Dong;  Zhou,Jing
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Ferroptosis  Lysosome  Quercetin  Ros  Transcription Factor Eb  
Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
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Drug Discovery  Malignant Melanoma  Pan-raf  S100b-p53 Interaction  Synergistic  
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes Journal article
Journal of Cellular Physiology, 2021,Volume: 236,Issue: 2,Page: 981-996
Authors:  Peng,Cheng;  Hou,Sheng Tao;  Deng,Chu Xia;  Zhang,Yandong
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Demethylation  Dhx33  Gadd45a  Glycolysis  Rna Helicase  Warburg Effect