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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Advanced sensitivity amplification strategies for voltammetric immunosensors of tumor marker: State of the art Journal article
Biosensors and Bioelectronics, 2021,Volume: 178
Authors:  Zheng,Yun;  Li,Jianding;  Zhou,Bingpu;  Ian,Hou;  Shao,Huaiyu
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Amplification strategies  Cascade reaction  Mesoporous silica  Signal species  Tumor markers  Voltammetric immunosensors  
Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
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challenge  combination therapy  immunotherapy  mechanism  NSCLC  PD-1/PD-L1  
Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
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challenge  combination therapy  immunotherapy  mechanism  NSCLC  PD-1/PD-L1  
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Oncogene, 2021,Volume: 40,Issue: 5,Page: 937-950
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen;  Shim,Joong Sup
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Polyphenol-Based Nanomedicine Evokes Immune Activation for Combination Cancer Treatment Journal article
Angewandte Chemie - International Edition, 2021,Volume: 60,Issue: 4,Page: 1967-1975
Authors:  Zhang,Zhan;  Sang,Wei;  Xie,Lisi;  Li,Wenxi;  Li,Bei;  Li,Jie;  Tian,Hao;  Yuan,Zhen;  Zhao,Qi;  Dai,Yunlu
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Combination Cancer Therapy  Gossypol  Metal–polyphenol Coordination  Nanomedicine  Pd-l1 Checkpoint Blockade  
Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
ACS Sensors, 2021
Authors:  Wu,Ke Jia;  Wu,Chun;  Chen,Feng;  Cheng,Sha Sha;  Ma,Dik Lung;  Leung,Chung Hang
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High-throughput screening  Iridium-based pH probe  Lysosomotropic compounds  Mitoxantrone  Time-resolved emission spectroscopy  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
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Aib1  Ecm  Hedgehog  Mafb  Pdac  
Oxygen-Evolving Manganese Ferrite Nanovesicles for Hypoxia-Responsive Drug Delivery and Enhanced Cancer Chemoimmunotherapy Journal article
Advanced Functional Materials, 2021
Authors:  Yang,Kuikun;  Yu,Guocan;  Tian,Rui;  Zhou,Zijian;  Deng,Hongzhang;  Li,Ling;  Yang,Zhen;  Zhang,Guofeng;  Liu,Dahai;  Wei,Jianwen;  Yue,Ludan;  Wang,Ruibing;  Chen,Xiaoyuan
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chemoimmunotherapy  drug delivery  hypoxia-responsive  self-assembly  
TNF–TNFR2 signal plays a decisive role in the activation of CD4+Foxp3+ Regulatory T Cells: Implications in the Treatment of Autoimmune Diseases and Cancer Book chapter
出自: Advances in Experimental Medicine and Biology, 2021, 页码: 257-272
Authors:  Islam,Md Sahidul;  Yang,Yang;  Chen,Xin
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Autoimmune diseases  Cancer  CD4+Foxp3+ regulatory T cells  TNF  TNFR2