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Pharmacological inhibition of KDM5A for cancer treatment Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 226
Authors:  Yang, Guan Jun;  Wu, Jia;  Miao, Liang;  Zhu, Ming Hui;  Zhou, Qian Jin;  Lu, Xin Jiang;  Lu, Jian Fei;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
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Cancer therapy  Drug resistance  Histone methylation  Lysine-specific demethylase 5A  Screening methods  
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Low, Heng Boon;  Wong, Zhen Lim;  Wu, Bangyuan;  Kong, Li Ren;  Png, Chin Wen;  Cho, Yik Lam;  Li, Chun Wei;  Xiao, Fengchun;  Xin, Xuan;  Yang, Henry;  Loo, Jia Min;  Lee, Fiona Yi Xin;  Tan, Iain Bee Huat;  DasGupta, Ramanuj;  Shen, Han Ming;  Schwarz, Herbert;  Gascoigne, Nicholas R.J.;  Goh, Boon Cher;  Xu, Xiaohong;  Zhang, Yongliang
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Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:  Zhao, Yuxin;  Wang, Haiyong;  He, Chengwei
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Drug resistance  Epidermal growth factor receptor-tyrosine kinase inhibitor  Non-small cell lung cancer  Targeted therapy  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
International Immunopharmacology, 2021,Volume: 101
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping;  Chen, Fengyang;  Alam, Md Masud;  Faustman, Denise L.;  Oppenheim, Joost J.;  Chen, Xin
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Antitumor  CD4+Foxp3+ regulatory T cells (Tregs)  HMGN1 and R848  Immunotherapy  TNFR2  
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao;  Bao, Jiaolin;  Zeng, Jianming;  Hao, Wenhui;  Sun, Heng;  Wong, Ada Hang Heng;  Valecha, Monica Vishnu;  Yang, Eun Ju;  Su, Sek Man;  Choi, Tak Kan;  Liu, Shuiming;  Chan, Kin Iong;  Yang, Ling Lin;  Wu, Jingbo;  Miao, Kai;  Chen, Qiang;  Shim, Joong Sup;  Xu, Xiaoling;  Deng, Chu Xia
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Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhang, Chao;  Li, Qingrui;  Qin, Guozheng;  Zhang, Yi;  Li, Chaoying;  Han, Liwen;  Wang, Rongchun;  Wang, Shudan;  Chen, Haixia;  Liu, Kechun;  He, Chengwei
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Anti-angiogenesis  Anti-metastasis  Hepatocellular carcinoma cells  NF-κB/MMP-9/VEGF pathway  Polyphyllin VII  
Characterization of nanoparticles combining polyamine detection with photodynamic therapy Journal article
Communications Biology, 2021,Volume: 4,Issue: 1
Authors:  Li, Wenting;  Wang, Lingyun;  Sun, Tianlei;  Tang, Hao;  Bui, Brian;  Cao, Derong;  Wang, Ruibing;  Chen, Wei
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Platinum-crosslinking polymeric nanoparticle for synergetic chemoradiotherapy of nasopharyngeal carcinoma Journal article
Bioactive Materials, 2021,Volume: 6,Issue: 12,Page: 4707-4716
Authors:  Ding, Yuxun;  Xiao, Xiaohui;  Zeng, Lingli;  Shang, Qiuping;  Jiang, Wei;  Xiong, Sha;  Duan, Xiaohui;  Shen, Jun;  Wang, Ruibing;  Guo, Jinshan;  Pan, Yue
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Chemoradiotherapy  Nasopharyngeal carcinoma (NPC)  Polymeric nanoparticles  Precise treatment  
Volume-based algorithm of lung dose optimization in novel dynamic arc radiotherapy for esophageal cancer Journal article
Scientific Reports, 2021,Volume: 11,Issue: 1
Authors:  Lin, Kuan Heng;  Hsu, Chen Xiong;  Wang, Shan Ying;  Mok, Greta S.P.;  Chang, Chiu Han;  Tien, Hui Ju;  Shueng, Pei Wei;  Wu, Tung Hsin
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