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Elevated NSD3 histone methylation activity drives squamous cell lung cancer Journal article
Nature, 2021
Authors:  Yuan,Gang;  Flores,Natasha M.;  Hausmann,Simone;  Lofgren,Shane M.;  Kharchenko,Vladlena;  Angulo-Ibanez,Maria;  Sengupta,Deepanwita;  Lu,Xiaoyin;  Czaban,Iwona;  Azhibek,Dulat;  Vicent,Silvestre;  Fischle,Wolfgang;  Jaremko,Mariusz;  Fang,Bingliang;  Wistuba,Ignacio I.;  Chua,Katrin F.;  Roth,Jack A.;  Minna,John D.;  Shao,Ning Yi;  Jaremko,Łukasz;  Mazur,Pawel K.;  Gozani,Or
Favorite |  | TC[WOS]:14 TC[Scopus]:12 | Submit date:2021/03/04
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/01
Brd4  BromoDomain Domain  Cell Metastasis And Invasion  Histone Acetylation  Melanoma  Protein–protein Interaction  Virtual Screening  
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2018/12/17
An iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent Journal article
Chemical Science, 2015,Volume: 6,Issue: 10,Page: 5400
Authors:  Zhong H.-J.;  Lu L.;  Leung K.-H.;  Wong C.C.L.;  Peng C.;  Yan S.-C.;  Ma D.-L.;  Cai Z.;  David Wang H.-M.;  Leung C.-H.
Favorite |  | TC[WOS]:103 TC[Scopus]:104 | Submit date:2018/10/30