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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
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Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
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Aib1  Ecm  Hedgehog  Mafb  Pdac  
Active-Targeting NIR-II Phototheranostics in Multiple Tumor Models Using Platelet-Camouflaged Nanoprobes Journal article
ACS Applied Materials and Interfaces, 2020,Volume: 12,Issue: 50,Page: 55624-55637
Authors:  Geng,Xiaorui;  Gao,Duyang;  Hu,Dehong;  Liu,Quanhong;  Liu,Chengbo;  Yuan,Zhen;  Zhang,Xuanjun;  Liu,Xin;  Sheng,Zonghai;  Wang,Xiaobing;  Zheng,Hairong
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Active Targeting  Multiple Tumor Models  Nir-ii  Photoacoustic Imaging  Photothermal Therapy  Platelet Cell Membrane  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
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Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
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Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
A digital microfluidic system with 3D microstructures for single-cell culture Journal article
Microsystems and Nanoengineering, 2020,Volume: 6,Issue: 1
Authors:  Zhai,Jiao;  Li,Haoran;  Wong,Ada Hang Heng;  Dong,Cheng;  Yi,Shuhong;  Jia,Yanwei;  Mak,Pui In;  Deng,Chu Xia;  Martins,Rui P.
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EZH2 overexpression dampens tumor-suppressive signals via an EGR1 silencer to drive breast tumorigenesis Journal article
Oncogene, 2020,Volume: 39,Issue: 48,Page: 7127-7141
Authors:  Guan,Xiaowen;  Deng,Houliang;  Choi,Un Lam;  Li,Zhengfeng;  Yang,Yiqi;  Zeng,Jianming;  Liu,Yunze;  Zhang,Xuanjun;  Li,Gang
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Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells Journal article
Nature Biomedical Engineering, 2020,Volume: 4,Issue: 11,Page: 1102-1116
Authors:  Li,Ling;  Zou,Jianhua;  Dai,Yunlu;  Fan,Wenpei;  Niu,Gang;  Yang,Zhen;  Chen,Xiaoyuan
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Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Cancer Letters, 2020,Volume: 490,Page: 1-11
Authors:  Huang,Bin;  Yip,Wai Kien;  Wei,Na;  Luo,Kathy Qian
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Acetyltanshinone IIA  Drug resistance  HER2 degradation  HER2-positive breast cancer