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Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu, Yun;  Wang, Honglian;  Wang, Xin;  Liu, Jiaqi;  Li, Junjian;  Wang, Xiang;  Zhang, Yun;  Bai, Zhigang;  Zhou, Qinghua;  Wu, Ying;  Shen, Yi;  Weng, Xiaoling;  Liu, Fatao;  Guo, Jiancheng;  Di, Lijun;  Gires, Olivier;  Zhang, Zhongtao;  Chen, Yiding;  Wang, Hongxia
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/09
Brca1/2  Breast Cancer  Cohort  Reclassification  Vus  
DNA damage repair system in C57BL/6 J mice is evolutionarily stable Journal article
BMC Genomics, 2021,Volume: 22,Issue: 1
Authors:  Wang, Xiaoyu;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Brca1  Brca2  C57bl/6 j  Dna Damage Repair  Evolution Selection  Variation  
Ethnic-specific BRCA1/2 variation within Asia population: Evidence from over 78 000 cancer and 40 000 non-cancer cases of Indian, Chinese, Korean and Japanese populations Journal article
Journal of Medical Genetics, 2021,Volume: 58,Issue: 11,Page: 752-759
Authors:  Bhaskaran, Shanmuga Priya;  Huang, Teng;  Rajendran, Barani Kumar;  Guo, Maoni;  Luo, Jiangtao;  Qin, Zixin;  Zhao, Bojin;  Chian, Jiasheng;  Li, Suicheng;  Wang, San Ming
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/12/08
Dna Repair  Genetic Heterogeneity  Genetic Predisposition To Disease  Genetic Variation  Genetics  Medical  
Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy Journal article
Advanced Science, 2021,Volume: 8,Issue: 21
Authors:  Lei, Josh Haipeng;  Lee, Mi Hye;  Miao, Kai;  Huang, Zebin;  Yao, Zhicheng;  Zhang, Aiping;  Xu, Jun;  Zhao, Ming;  Huang, Zenan;  Zhang, Xin;  Chen, Si;  Jiaying, N. G.;  Feng, Yuzhao;  Xing, Fuqiang;  Chen, Ping;  Sun, Heng;  Chen, Qiang;  Xiang, Tingxiu;  Chen, Lin;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/11/30
Brca1  Breast Cancer  Fgfr2 Inhibitor  Fgfr2-s252w  Tumor Slice Culture  
BRCA1 and BRCA2 Variation in Taiwanese General Population and the Cancer Cohort Journal article
Frontiers in Molecular Biosciences, 2021,Volume: 8
Authors:  Chian, Jiasheng;  Sinha, Siddharth;  Qin, Zixin;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
BRCA1  BRCA2  ethnicity  pathogenic  population  prevalence  
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen;  Hu, Lingling;  Su, Sek Man;  Chan, Un In;  Miao, Kai;  Zhang, Xu;  Zhang, Aiping;  Guo, Sen;  Chen, Si;  Meng, Ya;  Deng, Min;  Hao, Wenhui;  Lei, Haipeng;  Lin, Ying;  Yang, Zhonglin;  Tang, Dongjiang;  Wong, Koon Ho;  Zhang, Xiaohua Douglas;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/11/30
Brca1/BRCA1  Mammary tumor  Mrc2  Single cell RNA-seq  Tumor heterogeneity  
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2020/09/16
Framing Ethical Concerns and Attitudes towards Human Gene Patents in the Chinese Press Journal article
Asian Bioethics Review, 2020,Volume: 12,Issue: 3,Page: 307-323
Authors:  Li Du;  Sijie Lin;  Kalina Kamenova
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2020/12/04
Chinese Newspapers  Content Analysis  Human Gene Patents  Patentability  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite |  | TC[WOS]:14 TC[Scopus]:16 | Submit date:2020/09/16
Brca1  Breast Cancer  Dna Damage  Hdac  Histone Deacetylase  Reactive Oxygen Species  Synthetic Lethality  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:18 TC[Scopus]:20 | Submit date:2020/09/16
Atm-ampk-drp1  Brca1  Inflammasomes  Mitochondrial Dynamics  Mitophagy