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Notoginsenoside R1 intervenes degradation and redistribution of tight junctions to ameliorate blood-brain barrier permeability by Caveolin-1/MMP2/9 pathway after acute ischemic stroke Journal article
Phytomedicine, 2021,Volume: 90
Authors:  Liu, Bowen;  Li, Yiyang;  Han, Yan;  Wang, Shengpeng;  Yang, Hua;  Zhao, Yonghua;  Li, Ping;  Wang, Yitao
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/13
Acute Ischemic Stroke  Blood-brain Barrier  Caveolin1/mmp2/9 Pathway  Notoginsenoside R1  Tight Junctions  
Polymeric nanoparticles-based brain delivery with improved therapeutic efficacy of ginkgolide b in parkinson’s disease Journal article
International Journal of Nanomedicine, 2020,Volume: 15,Page: 10453-10467
Authors:  Zhao,Yuying;  Xiong,Sha;  Liu,Piaoxue;  Liu,Wei;  Wang,Qun;  Liu,Yao;  Tan,Hanxu;  Chen,Xiaojia;  Shi,Xuguang;  Wang,Qi;  Chen,Tongkai
Favorite |  | TC[WOS]:8 TC[Scopus]:10 | Submit date:2021/03/02
Blood–brain Barrier  Drug Delivery System  Endocytosis  Pd Treatment  Zebrafish  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2021/03/02
Ad Animal Models  Alzheimer's Disease  Clinical Trials  Egcg  Neuroprotective Effects  Systematic Review  
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong,Sha;  Li,Zhongjun;  Liu,Yao;  Wang,Qun;  Luo,Jingshan;  Chen,Xiaojia;  Xie,Zhongjian;  Zhang,Yuan;  Zhang,Han;  Chen,Tongkai
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2021/03/02
Black Phosphorus Nanosheets  Blood-brain Barrier  Brain Targeting  Drug Delivery  Lactoferrin  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
Alzheimer's disease  amyloid beta  cholinesterase  dual inhibition  
NIR-II-Activated Yolk-Shell Nanostructures as an Intelligent Platform for Parkinsonian Therapy Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 10,Page: 6876-6887
Authors:  Liu,Yao;  Zhu,Daoming;  Luo,Jingshan;  Chen,Xiaojia;  Gao,Liqian;  Liu,Wei;  Chen,Tongkai
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Blood-brain Barrier  Brain Drug Delivery  Gold Nanorods  Mesoporous Silica  Neurodegenerative Disorders  Nir-ii Biowindow  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2021/03/04
acetylcholinesterase  Alzheimer's disease  amyloid beta  butyrylcholinesterase  dual target inhibitor  isoquinolinium  pyridinium  
Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Xie,Youna;  Yan,Lingli;  Zeng,Haitao;  Chen,Weineng;  Lu,Jia Hong;  Wan,Jian Bo;  Su,Huanxing;  Yao,Xiaoli
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/01
Amyloid Beta  Aβ-degrading Enzymes  Neuroinflammation  Nf-κb  Omega-3 Polyunsaturated Fatty Acids  
Highly stabilized nanocrystals delivering Ginkgolide B in protecting against the Parkinson's disease Journal article
International Journal of Pharmaceutics, 2020,Volume: 577
Authors:  Liu,Yao;  Liu,Wei;  Xiong,Sha;  Luo,Jingshan;  Li,Ye;  Zhao,Yuying;  Wang,Qun;  Zhang,Zexin;  Chen,Xiaojia;  Chen,Tongkai
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2021/03/02
Blood-brain Barrier  Drug Delivery  Gastrointestinal Tract  Nanocrystals  Parkinson's Disease  
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease Journal article
Brain, Behavior, and Immunity, 2020,Volume: 85,Page: 35-45
Authors:  Yan,Lingli;  Xie,Youna;  Satyanarayanan,Senthil Kumaran;  Zeng,Haitao;  Liu,Qiang;  Huang,Miaodan;  Ma,Yuemeng;  Wan,Jian Bo;  Yao,Xiaoli;  Su,Kuan Pin;  Su,Huanxing
Favorite |  | TC[WOS]:11 TC[Scopus]:15 | Submit date:2021/03/01
Alzheimer's Disease  Beta-amyloid  Low-density LipoProtein Receptor-related Protein 1  Neuroinflammation  Omega-3 Polyunsaturated Fatty Acids