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Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs Journal article
Carbohydrate Polymers, 2021,Volume: 266
Authors:  Xiong, Wei;  Xiong, Shi Hang;  Chen, Qi Ling;  Linghu, Ke Gang;  Zhao, Guan Ding;  Chu, John M.T.;  Wong, Gordon T.C.;  Li, Juan;  Hu, Yuan Jia;  Wang, Yi Tao;  Yu, Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/13
Berberine  Brij-grafted-chitosan  Diabetic Kidney Disease  Oral Nanocarrier  P-glycoprotein  
Using Acetone/Water Binary Solvent to Enhance the Stability and Bioavailability of Spray Dried Enzalutamide/HPMC-AS Solid Dispersions Journal article
Journal of Pharmaceutical Sciences, 2021,Volume: 110,Issue: 3,Page: 1160-1171
Authors:  Zhang,Xiaoting;  Rao,Qiuhong;  Qiu,Zhenwen;  Lin,Yisheng;  Zhang,Lei;  Hu,Qingzhong;  Chen,Tingting;  Ma,Zhimin;  Gao,Hanlu;  Luo,Dandong;  Zhao,Jiaqi;  Ouyang,Defang;  Zhang,Zhenyu Jason;  Li,Qingguo
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Amorphous Solid Dispersion  Drug-excipient Interaction  Particle Size  Poorly Water-soluble Drug  Spray Drying  
In situ pepsin-assisted needle assembly of magnetic-graphitic-nanocapsules for enhanced gastric retention and mucus penetration Journal article
Nano Today, 2021,Volume: 36
Authors:  Cai,Xinqi;  Xu,Yiting;  Zhao,Lina;  Xu,Jiamei;  Li,Shengkai;  Wen,Chaoqi;  Xia,Xin;  Dong,Qian;  Hu,Xiaoxiao;  Wang,Xiaofeng;  Chen,Long;  Chen,Zhuo;  Tan,Weihong
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Gastric Retention  Harsh Gastric Environment  Magnetic-graphitic-nanocapsule Needle  Mucus Penetration  Pepsin-assisted Assembly  
Development of a Highly Water-Soluble Lycopene Cyclodextrin Ternary Formulation by the Integrated Experimental and Modeling Techniques Journal article
AAPS PharmSciTech, 2021,Volume: 22,Issue: 1
Authors:  Ma,Yan;  Zhong,Liuting;  Peng,Zhuo;  Liu,Xinyang;  Ouyang,Defang;  Guan,Shixia
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Bioavailability  Hot-melt Extrusion  Lycopene  Molecular Dynamics Simulation  Ternary Formulation  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
European Journal of Pharmaceutics and Biopharmaceutics, 2021,Volume: 158,Page: 336-346
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
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Dissolution Profile  Machine Learning  Molecular Dynamics (Md) Simulations  Pharmacokinetic Modeling  Solid Dispersion  
Integrated computer-aided formulation design: A case study of andrographolide/ cyclodextrin ternary formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2021
Authors:  Gao, Haoshi;  Su, Yan;  Wang, Wei;  Xiong, Wei;  Sun, Xiyang;  Ji, Yuanhui;  Yu, Hua;  Li, Haifeng;  Ouyang, Defang
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date:2021/10/02
Andrographolide  Cyclodextrins  Integrated computer-aided formulation design  Machine learning  Molecular dynamic simulation  Physiologically based absorption modeling  
Polymeric nanoparticles-based brain delivery with improved therapeutic efficacy of ginkgolide b in parkinson’s disease Journal article
International Journal of Nanomedicine, 2020,Volume: 15,Page: 10453-10467
Authors:  Zhao,Yuying;  Xiong,Sha;  Liu,Piaoxue;  Liu,Wei;  Wang,Qun;  Liu,Yao;  Tan,Hanxu;  Chen,Xiaojia;  Shi,Xuguang;  Wang,Qi;  Chen,Tongkai
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Blood–brain Barrier  Drug Delivery System  Endocytosis  Pd Treatment  Zebrafish  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
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Ad Animal Models  Alzheimer's Disease  Clinical Trials  Egcg  Neuroprotective Effects  Systematic Review  
Dietary polyphenols for managing cancers: What have we ignored? Journal article
Trends in Food Science and Technology, 2020,Volume: 101,Page: 150-164
Authors:  Wu,Xu;  Li,Mingxing;  Xiao,Zhangang;  Daglia,Maria;  Dragan,Simona;  Delmas,Dominique;  Vong,Chi Teng;  Wang,Yitao;  Zhao,Yueshui;  Shen,Jing;  Nabavi,Seyed Mohammad;  Sureda,Antoni;  Cao,Hui;  Simal-Gandara,Jesus;  Wang,Mingfu;  Sun,Chongde;  Wang,Shengpeng;  Xiao,Jianbo
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Anti-cancer Activity  Bioavailability  Dietary Polyphenols  Metabolites  Microbiota  Stability  
Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2020,Volume: 15,Issue: 4,Page: 518-528
Authors:  Xiong,Sha;  Liu,Wei;  Zhou,Yile;  Mo,Yousheng;  Liu,Yao;  Chen,Xiaojia;  Pan,Huafeng;  Yuan,Dongsheng;  Wang,Qi;  Chen,Tongkai
Favorite |  | TC[WOS]:9 TC[Scopus]:7 | Submit date:2021/03/02
Anti-parkinsonian Efficacy  Brain Permeability  Nanocrystals  Oral Absorption  Resveratrol