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In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Molecular Therapy - Oncolytics, 2020,Volume: 16,Page: 7-19
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.;  Kwok,Hang Fai
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/04
angiogenesis  anticancer peptides  antimicrobial peptides  apoptosis  drug discovery and development  molecular dynamics  targeted therapy  
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
Favorite |  | TC[WOS]:6 TC[Scopus]:7 | Submit date:2021/03/01
Antiangiogenesis  Apoptosis  Dietary compound  Glycyrrhetinic acid  Ovarian cancer  
The sphingosine kinase-1/sphingosine-1-phosphate axis in cancer: Potential target for anticancer therapy Journal article
Pharmacology and Therapeutics, 2019,Volume: 195,Page: 85-99
Authors:  Zheng,Xiangjin;  Li,Wan;  Ren,Liwen;  Liu,Jinyi;  Pang,Xiaocong;  Chen,Xiuping;  Kang,De;  Wang,Jinhua;  Du,Guanhua
Favorite |  | TC[WOS]:31 TC[Scopus]:30 | Submit date:2021/03/01
Cancer  Inhibitor  Mechanism  Sphingosine kinase 1  
Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas Journal article
Journal of Translational Medicine, 2019,Volume: 17,Issue: 1
Authors:  Sun X.;  Liu X.;  Xia M.;  Shao Y.;  Zhang X.D.
Adobe PDF | Favorite |  | TC[WOS]:13 TC[Scopus]:11 | Submit date:2021/03/03
Biomarker  Drug Resistance  Glioma  Macrophages  Multicellular Gene Network  Prognostic Signature  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
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Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 10,Page: 1389-1398
Authors:  Tan,Qiaoyan;  Wang,Zuqiang;  Wang,Quan;  Wang,Yuanqiang;  Huang,Zhifeng;  Su,Nan;  Jin,Min;  Kuang,Liang;  Qi,Huabing;  Ni,Zhenhong;  Li,Can;  Zhu,Ying;  Jiang,Wanling;  Chen,Hangang;  Deng,Chuxia;  Du,Xiao Lan;  Xie,Yang Li;  Chen,Lin
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2020/09/16
Cancer therapy  FGFR1  Lung cancer  Peptide  Phage display  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
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A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 10,Page: 1389-1398
Authors:  Tan, Qiaoyan;  Wang, Zuqiang;  Wang, Quan;  Wang, Yuanqiang;  Huang, Zhifeng;  Su, Nan;  Jin, Min;  Kuang, Liang;  Qi, Huabing;  Ni, Zhenhong;  Li, Can;  Zhu, Ying;  Jiang, Wanling;  Chen, Hangang;  Deng, Chuxia;  Du, Xiaolan;  Xie, Yangli;  Chen, Lin
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2018/10/30
Phage Display  Fgfr1  Peptide  Cancer Therapy  Lung Cancer  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B