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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Fluorescence resonance energy transfer-based sensor zebrafish for detecting toxic agents with single-cell sensitivity Journal article
Journal of Hazardous Materials, 2021,Volume: 408
Authors:  Jia,Hao;  Luo,Kathy Qian
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Cadmium  DNA-damaging agents  FRET imaging  In vivo apoptosis detection  ZnO nanoparticles  
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
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Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Modeling Uremic Vasculopathy With Induced Pluripotent Stem Cell-Derived Endothelial Cells as a Drug Screening System Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 8
Authors:  Jang,Hye Ryoun;  Cho,Hyung Joon;  Zhou,Yang;  Shao,Ning Yi;  Lee,Kyungho;  Le,Hoai Huong Thi;  Jeon,Junseok;  Lee,Jung Eun;  Huh,Wooseong;  Ong,Sang Ging;  Lee,Won Hee;  Kim,Yoon Goo
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Chronic Kidney Disease  Endothelial Cells  Induced Pluripotent Stem Cells  Uremic Toxin  Uremic Vasculopathy  
Development of a Highly Water-Soluble Lycopene Cyclodextrin Ternary Formulation by the Integrated Experimental and Modeling Techniques Journal article
AAPS PharmSciTech, 2021,Volume: 22,Issue: 1
Authors:  Ma,Yan;  Zhong,Liuting;  Peng,Zhuo;  Liu,Xinyang;  Ouyang,Defang;  Guan,Shixia
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bioavailability  hot-melt extrusion  lycopene  molecular dynamics simulation  ternary formulation  
LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 1
Authors:  Xiong,Minmin;  Wu,Mengshi;  Dan Peng,;  Huang,Weijun;  Chen,Zehong;  Ke,Haoxian;  Chen,Zewen;  Song,Wu;  Zhao,Yonghua;  Xiang,Andy P.;  Zhong,Xiaomin
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Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
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IFN-γ  Licochalcone A  Natural products  PD-L1  Protein synthesis inhibitor  ROS  
Emergence of spatio-temporal variations in chemotherapeutic drug efficacy: in-vitro and in-Silico 3D tumour spheroid studies Journal article
BMC Cancer, 2020,Volume: 20,Issue: 1
Authors:  Sheraton,M. V.;  Chiew,G. G.Y.;  Melnikov,V.;  Tan,E. Y.;  Luo,K. Q.;  Verma,N.;  Sloot,P. M.A.
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Cytotoxicity  Mitotic spindle stabilization  Pharmacodynamics  Pharmacokinetics  Reaction-diffusion model  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
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AD animal models  Alzheimer's disease  Clinical trials  EGCG  Neuroprotective effects  Systematic review  
Dissecting the mechanism of Yuzhi Zhixue granule on ovulatory dysfunctional uterine bleeding by network pharmacology and molecular docking Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Li,Jialin;  Luo,Hua;  Liu,Xinkui;  Zhang,Jingyuan;  Zhou,Wei;  Guo,Siyu;  Chen,Xiuping;  Liu,Yingying;  Jia,Shanshan;  Wang,Haojia;  Li,Bingbing;  Cheng,Guoliang;  Wu,Jiarui
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Mechanisms  Molecular Docking  Network pharmacology  Ovulatory Dysfunctional Uterine Bleeding  Yuzhi zhixue granule