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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
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B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy Journal article
Cell Reports, 2021,Volume: 34,Issue: 6
Authors:  Han,Congwei;  Song,Jinji;  Hu,Junqing;  Fu,Huijie;  Feng,Yanxian;  Mu,Ruoyu;  Xing,Zhen;  Wang,Zhenzhen;  Wang,Lintao;  Zhang,Junfeng;  Wang,Chunming;  Dong,Lei
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biofilm  cancer therapy  gut microbiome  probiotics  smectite  
Polyphenol-Based Nanomedicine Evokes Immune Activation for Combination Cancer Treatment Journal article
Angewandte Chemie - International Edition, 2021,Volume: 60,Issue: 4,Page: 1967-1975
Authors:  Zhang,Zhan;  Sang,Wei;  Xie,Lisi;  Li,Wenxi;  Li,Bei;  Li,Jie;  Tian,Hao;  Yuan,Zhen;  Zhao,Qi;  Dai,Yunlu
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Combination Cancer Therapy  Gossypol  Metal–polyphenol Coordination  Nanomedicine  Pd-l1 Checkpoint Blockade  
Pharmacological review of isobavachalcone, a naturally occurring chalcone Journal article
Pharmacological Research, 2021
Authors:  Wang,Miaojuan;  Lin,Ligen;  Lu,Jin Jian;  Chen,Xiuping
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Isobavachalcone  Molecular Targets  Pharmacokinetic  Pharmacology  
The drug likeness analysis of anti-inflammatory clerodane diterpenoids Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Feng,Zheling;  Cao,Jun;  Zhang,Qingwen;  Lin,Ligen
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Anti-inflammation  Clerodane diterpenoids  Drug-likeness  SwissADME  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
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BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells Journal article
Nature Biomedical Engineering, 2020,Volume: 4,Issue: 11,Page: 1102-1116
Authors:  Li,Ling;  Zou,Jianhua;  Dai,Yunlu;  Fan,Wenpei;  Niu,Gang;  Yang,Zhen;  Chen,Xiaoyuan
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Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Food Chemistry, 2020,Volume: 327
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie;  Zou,Liang;  Lu,Jin Jian
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Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Cancer Letters, 2020,Volume: 490,Page: 1-11
Authors:  Huang,Bin;  Yip,Wai Kien;  Wei,Na;  Luo,Kathy Qian
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Acetyltanshinone IIA  Drug resistance  HER2 degradation  HER2-positive breast cancer